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The aim of this study is to determine surgical outcomes and factors affecting seizure outcomes in patients who harbor supratentorial cavernous angiomas presenting with seizures. Sixty patients were classified into the intractable epilepsy group (n=22) and the sporadic seizure group (n=38) and then managed differently in accordance with our guidelines.(More)
OBJECTIVE The aim of the present study was to evaluate the usefulness of transcranial motor evoked potential (MEP) monitoring and its impact on morbidity after surgical clipping of unruptured intracranial aneurysms. METHODS Motor outcomes were compared before and after the application of MEP monitoring for a one year period. A total intravenous anesthesia(More)
PURPOSE The aim of this study was to evaluate clinico-radiological outcomes following gamma knife radiosurgery (GKS) for pediatric arteriovenous malformations (AVMs). METHODS The present series included 39 children (3-17 years of age) who underwent GKS for cerebral AVMs between January 2002 and February 2008. Twenty-five patients presented with(More)
BACKGROUND AND PURPOSE To evaluate the factors predictive of contralateral progression in children and adolescents with unilateral moyamoya disease (MMD), the authors retrospectively analyzed clinicoradiological findings. METHODS The records of 394 consecutive patients with MMD aged 0 to 17 years were reviewed. Unilateral MMD was defined based on the(More)
Autologous adult human neural stem cells may be used for regenerative cell therapies bypass potential ethical problems. However, stable in vitro expansion protocols and experimental/clinical factors influencing primary cultures need to be further elucidated for clinically applicable techniques. To address these issues, we obtained biopsy specimens from 23(More)
BACKGROUND Both Moyamoya disease (MMD) and intracranial atherosclerotic stenosis (ICAS) are more prevalent in Asians than in Westerners. We hypothesized that a substantial proportion of patients with adult-onset MMD were misclassified as having ICAS, which may in part explain the high prevalence of intracranial atherosclerotic stroke in Asians. METHOD We(More)
BACKGROUND Both basal collaterals (BC) and cortical microvascularization (CM) on angiography have been suggested as moyamoya disease (MMD)-specific findings; however, it is unknown whether the vascular network represents compensatory mechanisms for vascular occlusion or aberrant active neovascularization. METHODS We investigated the grade of antegrade MCA(More)
BACKGROUND Major artery aneurysms may be found incidentally while evaluating moyamoya disease (MMD). The purpose of this study was to delineate the prevalence and characteristics of these uncommon aneurysms with a brief mention of their management and outcomes. METHODS We conducted a retrospective review of 249 adult patients who were diagnosed with(More)
OBJECTIVE Chronic subdural hematoma (CSDH) is a rare complication of unruptured aneurysm clipping surgery. The purpose of this study was to identify the incidence and risk factors of postoperative CSDH after surgical clipping for unruptured anterior circulation aneurysms. METHODS This retrospective study included 518 patients from a single tertiary(More)
PURPOSE The aim of the present study was to delineate preoperative factors that may predict perforator injuries following open surgery for an unruptured middle cerebral artery (MCA) aneurysm. METHODS The authors conducted a retrospective review of 85 consecutive patients who underwent surgical clipping of 91 unruptured MCA aneurysms. In addition to(More)