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Since human papillomavirus (HPV) E6 and E7 are promising tumor antigens, we engineered E6 and E7 antigens to generate an optimal HPV DNA vaccine by codon optimization (Co), fusion of E6 and E7, addition of a tissue plasminogen activator (tpa) signal sequence, addition of CD40 ligand (CD40L) or Fms-like tyrosine kinase-3 ligand (Flt3L). The resulting(More)
BACKGROUNDS AND OBJECTIVES The aim of the study was to measure the spectral dependence of optical absorption and reduced scattering coefficients and thermal conductivity and diffusivity of porcine nasal septal cartilage. Values of optical and thermal properties determined in this study may aid in determining laser dosimetry and allow selection of an optical(More)
We demonstrate the application of an infrared (IR) imaging technique for non-contact determination of thermal diffusivity in biological materials. The proposed method utilizes pulsed laser excitation to produce an initial three-dimensional temperature distribution in tissue, and records IR images of subsequent heat diffusion. The theoretical model assumes(More)
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