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PURPOSE To develop a new foveal hypoplasia grading system using optical coherence tomography (OCT) and to determine the correlations of visual acuity to the iris transillumination, macular transparency, and foveal hypoplasia grades, respectively, in young albinism patients. DESIGN Observational case series. PARTICIPANTS Thirteen patients who were(More)
PURPOSE To compare the features of localized retinal nerve fiber layer (RNFL) defects between a low-teen intraocular pressure (IOP) group and a high-teen IOP group in normal-tension glaucoma (NTG) patients. METHODS Seventy-seven eyes of 77 NTG patients showing localized RNFL defects on RNFL photographs and corresponding visual filed defects at the initial(More)
A 44-year-old woman who showed recurrent vitreous hemorrhages with vascular tortuosity received CT angiography which revealed an internal carotid artery aneurysm. A case of internal carotid aneurysm was associated with a pattern of retinal arteriolar tortuosity pathognomic for familial retinal arterial tortuosity (fRAT), suggesting possible involvement of(More)
PURPOSE To determine the timing of spontaneous venous pulsation (SVP) relative to the ocular circulatory cycle by using the movie tool of confocal scanning laser ophthalmoloscope. METHODS A video recording of the fundus was obtained using a confocal scanning laser ophthalmoscope (Spectralis HRA, Heidelberg Engineering, Heidelberg, Germany) at 8 frames/s(More)
A case of Vogt-Koyanagi-Harada disease (VKH) that developed in a 36-year-old woman with Graves' disease was described. The patient was treated with Lugol's solution and presented with bilateral serous retinal detachment. She had also suffered from methimazole-induced hypersensitivity and steroid-induced myopathy. Fluorescein angiography showed multiple(More)
Idiopathic infantile nystagmus (IIN) is the involuntary oscillation of the eyes with onset in the first few months of life. The most common form of inheritance is X-linked, and mutations in FRMD7 gene are a major cause. To identify the FRMD7 gene mutations associated with X-linked IIN, we performed PCR-based DNA direct sequencing in 4 affected subjects from(More)
PURPOSE To compare the effect of early versus late intravitreal injection of triamcinolone in patients with macular edema due to branch retinal vein occlusion (BRVO). METHODS Twenty eyes of 20 patients with macular edema from BRVO, including 10 with duration after onset of or <or= 3 months and 10 with duration of 3 months, were treated using a single(More)
PURPOSE To investigate the relationship of intraocular pressure (IOP) and the frequency of spontaneous venous pulsation (SVP) in primary open-angle glaucoma (POAG). DESIGN Cross-sectional study. PARTICIPANTS A total of 229 eyes of 229 patients with POAG and 205 eyes of 205 glaucoma suspects as a control. METHODS The SVP was assessed using a confocal(More)
PURPOSE To determine the relationship between the American Medical Association's (AMA) functional vision score (FVS) and vision-specific quality of life in retinitis pigmentosa (RP) patients using the National Eye Institute's Visual Functioning Questionnaire (NEI-VFQ 25). METHODS One hundred eight patients with RP participated in the study. We measured(More)
PURPOSE To investigate if antituberculosis medication including ethambutol could be a possible epigenetic factor in visual loss in Leber's hereditary optic neuropathy (LHON). METHODS The authors reviewed the medical records of 46 patients registered at Bundang Seoul National University Hospital from 2002 to 2006, who developed the typical clinical(More)