Jc Pineda

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Currently, there is no definitive diagnostic test for traumatic brain injury (TBI) to help physicians determine the seriousness of injury or the extent of cellular pathology. Calpain cleaves alphaII-spectrin into breakdown products (SBDP) after TBI and ischemia. Mean levels of both ipsilateral cortex (IC) and cerebral spinal fluid (CSF) SBDP at 2, 6, and 24(More)
Proteolytic processing plays an important role in regulating a wide range of important cellular functions, including processing of cytoskeletal proteins. Loss of cytoskeletal proteins such as spectrin is an important characteristic in a variety of acute central nervous system injuries including ischemia, spinal cord injury and traumatic brain injury (TBI).(More)
  • Jm Alisky, Alfaro Jl, Alvarez-Cervera Fj, Jc Pineda, G Arankowksy-Sandoval, Heredia-Lopez F +5 others
  • 2006
To the Editor—Sedation is a common side-effect of drugs used to treat Parkinson's disease, especially anticholinergic and dopaminergic drugs. Caffeine and methylphenidate may alleviate this sedation and improve the treatment of Parkinson's disease. Two case histories provided the initial basis for this idea. The first patient was a healthy adult who(More)
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