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Antimicrobial activity of marine bacteria associated with sponges from the waters off the coast of South East India.
TLDR
This is the first report on phylogenetic identification of antibiotic producing bacteria associated with sponges from Indian waters and a preponderance of bacteria belonging to Vibrio and Bacillus genera with 95-99% sequence similarities are indicated. Expand
Molecular analyses of microbial diversity associated with the Lonar soda lake in India: an impact crater in a basalt area.
TLDR
Diversity analyses demonstrate greater diversity and evenness of bacterial species compared to a skewed representation of species for Archaea and a comparatively less diverse archaeal population. Expand
Molecular typing of fecal eukaryotic microbiota of human infants and their respective mothers
TLDR
The investigation is the first of its kind in the comparative study of the human feces to reveal the presence of micro-eukaryotic diversity variance in infants and adults from the Indian subcontinent and revealed that the infants did not seem to harbour any micro- eukaryotes in their gut. Expand
High fat diet drives obesity regardless the composition of gut microbiota in mice
TLDR
It is demonstrated that gut microbiota is involved in the regulation of glucose metabolism and the abundance of Bacteroidetes significantly modulates HF-induced glucose intolerance but has limited impact on obesity in mice, and individual microbiota composition may cause phenotypic variation associated with HF feeding in mice. Expand
Host Genetics and Environmental Factors Regulate Ecological Succession of the Mouse Colon Tissue-Associated Microbiota
TLDR
The association of Nod2 genotype (and other host polymorphisms) and environmental factors likely combine to influence the ecological succession of the tissue-associated microflora accounting in part for their association with the pathogenesis of inflammatory bowel diseases. Expand
A Western Diet Ecological Module Identified from the ‘Humanized’ Mouse Microbiota Predicts Diet in Adults and Formula Feeding in Children
TLDR
This study provides a conceptual platform to translate microbial ecology from preclinical models to humans and identifies an ecological network module underlying the association of the gut microbiota with Western dietary habits. Expand
Modeling Longitudinal Metabonomics and Microbiota Interactions in C57BL/6 Mice Fed a High Fat Diet.
TLDR
The use of multilevel simultaneous component analysis (MSCA), orthogonal projection on latent structures (OPLS), and regularized canonical correlation analysis (rCCA) to study associations between specific longitudinal urine metabonomics data and microbiome data in a diet-induced obesity model using C57BL/6 mice is reported. Expand
Aging and sarcopenia associate with specific interactions between gut microbes, serum biomarkers and host physiology in rats
TLDR
It is demonstrated that aging skews the composition of the gut microbiome, in particular by altering the Sutterella to Barneseilla ratio, and alters the metabolic potential of intestinal bacteria, and provides candidate microbial species to target physical and metabolic decline during aging by modulating gut microbial ecology. Expand
Transcriptomics-driven lipidomics (TDL) identifies the microbiome-regulated targets of ileal lipid metabolism
The gut microbiome and lipid metabolism are both recognized as essential components in the maintenance of metabolic health. The mechanisms involved are multifactorial and (especially for microbiome)Expand
Cohort Specific Effects of Cereal-bar Supplementation in Overweight Patients With or Without Type 2 Diabetes Mellitus
TLDR
The data indicate that responses to cereal-bar supplementation are cohort specific and this should be considered when manipulating the microbiome via diet supplementation. Expand
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