Jay M Mil Stein

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Drug and alcohol abusers, psychiatric patients, and those with neurologic dysfunction represent a large proportion of burn victims, but little is known about the impact of these conditions on burn morbidity. We wanted to determine whether this group has more complications, more surgical procedures, and longer hospital stays than other burn patients. We also(More)
One hr following an infusion of 3H-L-tryptophan, the lateral hypothalamus was perfused with physiological bacteriostatic saline for 40 min. Samples of perfusate, which corresponded to 75--90 min post-infusion, were analyzed by thin layer chromatography for estimation of 3H-labelled L-tryptophan, 5-hydroxytryptophan and 5-hydroxytryptamine. The results(More)
The cardiovascular (CV) responses to an acute emotional situation in unanesthetized, chair-restrained baboons include elevations in heart rate, blood pressure, and terminal aortic flow and a complex biphasic reduction in renal flow. The same CV responses can be produced by stimulating an area in the hypothalamus. Furthermore, bilateral ablation of the(More)
The distribution of eating, drinking and body weight changes during the 24 hr day were examined following brain 5-HT depletion with p-chloroamphetamine (PCA). Following a baseline period, measurements of food and water intakes and body weights were recorded 1, 2, 3, 6, 12, 20 and 24 hr following PCA, 5.0 mg/kg, or saline. Other animals were pretreated with(More)
A community’s history, as represented in the cultural and built environment, can serve as an important asset for economic development and sustainable stewardship. Challenges abound in linking historic preservation and community economic development, especially in communities at risk of losing their unique character and attempting to protect their special(More)
Para-chloramphetamine (PCA) is a drug whose long-term and short-term neurochemical and behavioral effects have received considerable attention. The purpose of the present study was to determine whether PCA produces acute urination, defecation, and body weight changes similar to that seen following various amphetamine derivatives. Following baseline test(More)
These studies examined the effects of altered activity or levels of serotonin (5-HT) in the central nervous system (CNS) on renal water and excretion of electrolytes and on arterial blood pressure. Rats were implanted with intracerebroventricular cannulae and then continuously hydrated with a hypotonic solution in order to induce a diuresis. In two separate(More)
We describe the use of the simple bone curet for the purpose of scraping and debriding partial-thickness burn wounds and other chronic wounds encountered by the burn surgeon before autograft placement. In our experience the instrument allows more efficient and safer operating room debridement than does the standard scalpel blade.
One hour following an infusion of 3H-5-hydroxytryptamine, animals were injected with either 15 mg/kg imipramine hydrochloride or 0.9% NaCl and then the lateral hypothalamus was perfused for 40 min. Samples of perfusate were analyzed by thin layer chromatography for estimation of 3H-labelled 5-hydroxytryptamine and metabolites. The results indicate that(More)