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DNA methylation and dimethylation of lysine 9 of histone H3 (H3K9me2) are two chromatin modifications that can be associated with gene expression or recombination rate. The maize genome provides a complex landscape of interspersed genes and transposons. The genome-wide distribution of DNA methylation and H3K9me2 were investigated in seedling tissue for the(More)
Both transcriptional and epigenetic regulations are fundamental for the control of eukaryotic gene expression. Here we perform a compendium analysis of >200 large sequencing data sets to elucidate the regulatory logic of global gene expression programs in mouse embryonic stem (ES) cells. We define four major classes of DNA-binding proteins (Core, PRC, MYC(More)
Assigning global unique persistent identifiers (GUPIs) to datasets has the goal of improving their accessibility and simplifying how they are referenced and reused. However, as repositories receive more and complex data, attesting for the identity of datasets attached to persistent identifiers over time is becoming more challenging. This is due to the(More)
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