Javier Martínez Rodríguez

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The infectivity of rotavirus, the main causative agent of childhood diarrhea, is dependent on activation of the extracellular viral particles by trypsin-like proteases in the host intestinal lumen. This step entails proteolytic cleavage of the VP4 spike protein into its mature products, VP8* and VP5*. Previous cryo-electron microscopy (cryo-EM) analysis of(More)
The strain BA71V has played a key role in African swine fever virus (ASFV) research. It was the first genome sequenced, and remains the only genome completely determined. A large part of the studies on the function of ASFV genes, viral transcription, replication, DNA repair and morphogenesis, has been performed using this model. This avirulent strain was(More)
1. Abstract The interest of having applications that can be remotely monitored and managed has increased with the generalised use of networks in all the computer environments. However, this integration is not always an easy work, mainly thinking that the analysts and developers skills usually do not cover this area. Applicaton Monitoring Architecture (AMA),(More)
The mechanisms involved in the construction of the icosahedral capsid of the African swine fever virus (ASFV) particle are not well understood at present. Capsid formation requires protein p72, the major capsid component, but other viral proteins are likely to play also a role in this process. We have examined the function of the ASFV structural protein(More)
(1997) Detection of mRNAs encoding peroxisomal proteins by non-radioactive in situ hybridization with digoxigenin-labelled cRNAs. Target and signal amplification: approaches to increase the sensitivity of in situ hybridization. (1990) Expresson of type VI procollagen and prolyl 4-hydroxylase mRNA in carbon tetrachloride induced liver fibrosis studied by in(More)
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