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Structured abstract Context. A software artefact typically makes its functionality available through a specialized Application Programming Interface (API) describing the set of services offered to client applications. In fact, building any software system usually involves managing a plethora of APIs, which complicates the development process. In(More)
Model-driven engineering techniques can be used both to create new software and to modernize existing software systems. Model-driven software modernization requires a first step for the extraction of models. Most modernization scenarios involve dealing with the GPL source code of the existing system. Techniques and tools providing efficient means to extract(More)
Data rather than functionality are the sources of competitive advantage for Web2.0 applications such as wikis, blogs and social networking websites. This valuable information might need to be capitalized by third-party applications or be subject to migration or data analysis. Model-Driven Engineering (MDE) can be used for these purposes. However, MDE first(More)
The widespread replicons of repABC and repC families from alpha-proteobacteria share high similarity in their replication initiator proteins (RepC). Here we describe the minimal region required for stable replication of a member of the repC family, the low copy-number plasmid pRmeGR4a from Sinorizobium meliloti GR4. This region contains only two genes: one(More)
In this paper, we report the identification of replication/partition regions of plasmid p42a and p42b of Rhizobium etli CFN42. Sequence analysis reveals that both replication/partition regions belong to the repABC family. Phylogenetic analysis of all the complete repABC replication/partition regions reported to date, shows that repABC plasmids coexisting in(More)
Acute stroke services have been installed in most hospitals in the industrialized world, and dealing with hyperacute stroke has become one of the most frequently performed tasks of the on-call radiologist. Imaging plays a key role in current guidelines for thrombolysis, and knowledge of classic early ischemic signs or depiction of hemorrhage at nonenhanced(More)
Computed tomography (CT)-guided biopsy of the spine is considered a safe, accurate, and relatively inexpensive examination technique. Our purpose was to determine the diagnostic accuracy of CT-guided biopsies exclusively for vertebral osteomyelitis. A retrospective study was performed from a consecutive series of 72 patients with confirmed vertebral(More)
As cloud computing allows improving the quality of software and aims at reducing costs of operating software, more and more software is delivered as a service. However, moving from a software as a product strategy to delivering software as a service hosted in cloud environments is very ambitious. This is due to the fact that managing software modernization(More)
A cross-sectional evaluation of dental caries in primary teeth and nutritional status was conducted involving 285 Peruvian children from low socioeconomic conditions aged 3-9 y. Forty-nine percent of the children were found to be chronically malnourished (stunted) whereas acute malnutrition (wasting) was infrequent (2%). Stunted children showed a delayed(More)
HAL is a multidisciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L'archive ouverte pluridisciplinaire HAL, est destinée au dépôt età la diffusion(More)