Javier Lopez San Martin

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Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci

Adrian Cortes, Johanna S. Hadler, +62 authors Matthew A Brown
Nature Genetics
2013

Ankylosing spondylitis is a common, highly heritable inflammatory arthritis affecting primarily the spine and pelvis. In addition to HLA-B*27 alleles, 12 loci have previously been identified that are… (More)

Evolution of the Sabin strain of type 3 poliovirus in an immunodeficient patient during the entire 637-day period of virus excretion.

Javier Lopez San Martin, Glynis Dunn, Roger Hull, Vipul Hiralal Patel, Philip D. Minor
Journal of virology
2000

A 20-year-old female hypogammaglobulinemic patient received monotypic Sabin 3 vaccine in 1962. The patient excreted type 3 poliovirus for a period of 637 days without developing any symptoms of… (More)

Co-Circulation and Evolution of Polioviruses and Species C Enteroviruses in a District of Madagascar

Mala Rakoto-Andrianarivelo, Sophie Guillot, +9 authors Françis Delpeyroux
PLoS pathogens
2007

Between October 2001 and April 2002, five cases of acute flaccid paralysis (AFP) associated with type 2 vaccine-derived polioviruses (VDPVs) were reported in the southern province of the Republic of… (More)

Studies of the binding properties of influenza hemagglutinin receptor-site mutants.

Javier Lopez San Martin, Steve A. Wharton, +4 authors David A. Steinhauer
Virology
1998

Site-specific mutations have been made in the influenza hemagglutinin (HA) receptor binding site to assess the contribution of individual amino acid residues to receptor recognition. Screening of… (More)

High-grade inflammation, circulating adiponectin concentrations and cardiovascular risk factors in severe rheumatoid arthritis.

M A González-Gay, Javier Llorca, +7 authors Patrick H Dessein
Clinical and experimental rheumatology
2008

OBJECTIVE To assess whether obesity and systemic inflammation are potential determinants of circulating adiponectin concentrations and whether low adiponectin levels cluster with metabolic syndrome… (More)

Metagenome of the Mediterranean deep chlorophyll maximum studied by direct and fosmid library 454 pyrosequencing

Rohit Ghai, Ana-Belén Martín-Cuadrado, +9 authors Francisco Rodríguez-Valera
The ISME Journal
2010

The deep chlorophyll maximum (DCM) is a zone of maximal photosynthetic activity, generally located toward the base of the photic zone in lakes and oceans. In the tropical waters, this is a permanent… (More)

Correction: Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy

Olga Y. Gorlova, Javier Martin, +66 authors Javier Lopez San Martin
2011

The aim of this study was to determine, through a genome-wide association study (GWAS), the genetic components contributing to different clinical sub-phenotypes of systemic sclerosis (SSc). We… (More)

Rapid detection of CFTR gene rearrangements impacts on genetic counselling in cystic fibrosis.

Florence Niel, Javier Lopez San Martin, +5 authors Emmanuelle Girodon
Journal of medical genetics
2004

C ystic fibrosis (CF) (MIM 219700) is one of the most common autosomal recessive diseases in Caucasians. It affects about 1 in 2500 births and approximately 1 in 25 individuals are heterozygotes,… (More)

In vitro infection of human peripheral blood mononuclear cells by GB virus C/Hepatitis G virus.

Marta Fogeda, Sonia Navas, +4 authors Vicente Carreño
Journal of virology
1999

GB virus C (GBV-C), also known as hepatitis G virus, is a recently discovered flavivirus-like RNA agent with unclear pathogenic implications. To investigate whether human peripheral blood mononuclear… (More)

Identification of a new putative functional IL18 gene variant through an association study in systemic lupus erythematosus.

Elena Sánchez, Rogelio Jesus Palomino-Morales, +11 authors Javier Lopez San Martin
Human molecular genetics
2009

Interleukin-18 (IL-18) is a proinflammatory cytokine that plays an important role in chronic inflammation and autoimmune disorders. In this study, we aimed to determine the potential role of the IL18… (More)

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