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The aims of this study were to functionally characterize and analyze the transcriptional regulation and transcriptome of the Rhizobium etli rpoE4 gene. An R. etli rpoE4 mutant was sensitive to oxidative, saline, and osmotic stresses. Using transcriptional fusions, we determined that RpoE4 controls its own transcription and that it is negatively regulated by(More)
Metastasis is the leading cause of death in cancer patients. Cell motility is believed to be a necessary step in the metastatic process (L. Liotta and W. G. Stetler-Stevenson, In: Cancer: Principles and Practice of Oncology, pp. 134-149, 1993). Currently, most methods available to study the behavior of metastatic tumor cells are indirect, e.g., cell(More)
BACKGROUND Copines are soluble, calcium-dependent membrane binding proteins found in a variety of organisms. Copines are characterized as having two C2 domains at the N-terminal region followed by an "A domain" at the C-terminal region. The "A domain" is similar in sequence to the von Willebrand A (VWA) domain found in integrins. The presence of C2 domains(More)
This work proposes a system for the automatic annotation and monitoring of cell phone activity and stress responses of users. While mobile phone applications (e.g., e mail, voice, calendar) are used to non-intrusively extract the context of social interactions, a non-intrusive and comfortable biosensor is used to measure the electrodermal activity (EDA).(More)
Members of the genus Leptospirillum are aerobic iron-oxidizing bacteria belonging to the phylum Nitrospira. They are important members of microbial communities that catalyze the biomining of sulfidic ores, thereby solubilizing metal ions. These microorganisms live under extremely acidic and metal-loaded environments and thus must tolerate high(More)
We propose a new approach to perform classification in the presence of large amounts of irrelevant or noisy instances. This is achieved by designing a convex objective function whose optimization finds the most relevant samples for classification, and uses them to discriminate between classes. In particular, we combine the logistic loss with a combination(More)
Understanding if a movement is being executed correctly is important to a number of manipulation tasks. We present a preliminary study using inertial measurement units (IMUs) to evaluate the correct execution of squash swings, as well as discriminating them from similar racquet sport swings such as tennis and badminton. Additionally, we will show some(More)
The purpose of this work is to explore the use of Conditional Random Fields (CRFs) in the automatic recognition of the basic units of facial expression, described by the Facial Action Coding System (FACS) as Action Units (AU). Facial expression recognition is a complex problem aggravated by (1) variability between the subjects and (2) variability in the(More)
Phosphorylation of the alpha-subunit of eukaryotic initiation factor 2 (eIF-2) is one of the best known mechanisms regulating protein synthesis in a wide range of eukaryotic cells, from yeast to human. To determine whether this mechanism operates in primary neuronal cells, we have cultured primary neuronal cells for 7 days under two optimal growing(More)
The initial step of protein synthesis is regulated by the eukaryotic initiation factor 2 (eIF-2) whose phosphorylation in the alpha subunit by specific kinases, as double-stranded RNA-dependent protein kinase (PKR), produces an inhibition of the translational rates. Besides, intracellular Ca2+ mobilization has been associated with an increase in the PKR(More)
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