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Genomewide Association Study of Severe Covid-19 with Respiratory Failure
TLDR
A 3p21.31 gene cluster is identified as a genetic susceptibility locus in patients with Covid-19 with respiratory failure and a potential involvement of the ABO blood-group system is confirmed. Expand
Solidification/stabilization of toxic metals in calcium aluminate cement matrices.
The ability of calcium aluminate cement (CAC) to encapsulate toxic metals (Pb, Zn and Cu) was assessed under two curing conditions. Changes in the consistency and in the setting time were found uponExpand
Clinical features, ventilatory management, and outcome of ARDS caused by COVID-19 are similar to other causes of ARDS
TLDR
In this large series, COVID-19 ARDS patients have features similar to other causes of ARDS, compliance with lung-protective ventilation was high, and the risk of 28-day mortality increased with the degree of AR DS severity. Expand
Prognostic factors associated with mortality risk and disease progression in 639 critically ill patients with COVID-19 in Europe: Initial report of the international RISC-19-ICU prospective
TLDR
The European RISC-19-ICU cohort demonstrates a moderate mortality of 24% in critically ill patients with COVID-19, and Elevated risk of bloodstream infections underscores the need to exercise caution with off-label therapies. Expand
Piperacillin population pharmacokinetics in critically ill patients with multiple organ dysfunction syndrome receiving continuous venovenous haemodiafiltration: effect of type of dialysis membrane on
TLDR
The results suggest that type of membrane and body weight should be considered for piperacillin dose titration in critically ill patients with MODS and CVVHDF requirement. Expand
Linezolid Pharmacokinetics in Patients With Acute Renal Failure Undergoing Continuous Venovenous Hemodiafiltration
TLDR
Continuous renal replacement therapy (CRRT) runs continuously over a 24-hour period and allows greater hemodynamic stability, is better tolerated, and permits accurate blood volume control, which could be beneficial in some patients. Expand
Study on the effectiveness of PNS and LS superplasticizers in air lime-based mortars
Abstract Polynaphtalenesulfonate (PNS) and lignosulfonate (LS) were tested as superplasticizers in pastes and mortars of pure air lime and air lime with a pozzolanic additive, nanosilica (NS). LSExpand
Awake prone positioning does not reduce the risk of intubation in COVID-19 treated with high-flow nasal oxygen therapy: a multicenter, adjusted cohort study
TLDR
In patients with COVID-19 ARF treated with HFNO, the use of awake-PP did not reduce the need for intubation or affect mortality. Expand
Predictors of failure with high-flow nasal oxygen therapy in COVID-19 patients with acute respiratory failure: a multicenter observational study
TLDR
Among adult critically ill patients with COVID-19 initially treated with HFNO, the SOFA score and the ROX index may help to identify patients with higher likelihood of intubation. Expand
Randomized, multicenter trial of lateral Trendelenburg versus semirecumbent body position for the prevention of ventilator-associated pneumonia
TLDR
The LTP slightly decreased the incidence of microbiologically confirmed VAP, but at this time, the LTP cannot be recommended as a VAP preventive measure. Expand
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