Javier Cerezo

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Early hypothyroidism produces a generalized damage in the brain and in particular, changes in the connectivity of neocortical sensory areas. In this paper, the potential alterations in local neocortical circuits have been explored using immunocytochemistry for parvalbumin (PV) in normal and hypothyroid adult rats. The number and radial distribution of(More)
RATIONALE Noncompliance with vaccination schedules undermines the potential benefits of immunization. The purpose of this study was to evaluate whether a reminder of the next vaccine dose sent by the Short Messaging Service (SMS) to the vaccinee's mobile phone increases compliance with hepatitis A + B and hepatitis A vaccination schedule. SUBJECTS AND(More)
A complex mechanical-biological waste treatment plant designed for the processing of mixed municipal solid wastes (MSW) and source-selected organic fraction of municipal solid wastes (OFMSW) has been studied by using stability indices related to aerobic (respiration index, RI) and anaerobic conditions (biochemical methane potential, BMP). Several selected(More)
The size of any axon is generally related to an internal programme (probably common for all neurones) that determines the number and organization of its cytoskeletal components. Here we show that axons from visually deprived rats are smaller than controls, although the number of microtubules and neurofilaments remains unchanged. Moreover the distance(More)
A monoclonal antibody, mAb 44D5, has been used to identify and clone Drosophila syntaxin 1 (Dsynt1), an homologue of rat syntaxin 1. The deduced amino acid sequence of the Dsynt1 cDNA cloned is highly homologous to rat syntaxin 1A. Dsynt1 contains 291 amino acid residues and like other members of the syntaxin family is an integral membrane protein, with a(More)
In this work, we investigate systems formed by β-carotene and zeaxanthin embedded separately in a model lipid bilayer of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) through molecular dynamics (MD) simulations. The study is conducted using an all-atoms model and by analyzing the structural changes that occur at both the carotenoid molecule and the(More)
We simulate from first-principles the absorption spectra of five structure-related coumarin derivatives utilized in dye sensitized solar cells (DSSCs), investigating the vibronic and solvent contributions to the position and width of the spectra in ethanol. Ground and excited state potential energy surfaces (PESs) are modeled by Density Functional Theory(More)
When large structural displacements take place between the ground state (GS) and excited state (ES) minima of polyatomic molecules, the choice of a proper set of coordinates can be crucial for a reliable simulation of the vibrationally resolved absorption spectrum. In this work, we study two carotenoids that undergo structural displacements from GS to ES(More)
We study the absorption and emission electronic spectra in an aqueous solution of N-methyl-6-oxyquinolinium betaine (MQ), an interesting dye characterized by a large change of polarity and H-bond ability between the ground (S0) and the excited (S1) states. To that end we compare alternative approaches based either on explicit solvent models and density(More)
The clinical use of platinum(II)-based drugs incurs serious side effects due to the non-specific reactions with both malignant and normal cells. To circumvent such major drawback, novel metallodrugs might be combined with suitable carrier molecules, as antibodies, to ensure selective attacks on tumors while sparing healthy tissues. In this contribution, we(More)