Jaume M. Canaves

Sort by:

Shotgun crystallization strategy for structural genomics: an optimized two-tiered crystallization screen against the Thermotoga maritima proteome.

Rebecca Page, Slawomir K. Grzechnik, +5 authors Scott A. Lesley
Acta crystallographica. Section D, Biological…
2003

As the field of structural genomics continues to grow and new technologies are developed, novel strategies are needed to efficiently crystallize large numbers of protein targets, thus increasing… (More)

Circular dichroism spectra of human hemoglobin reveal a reversible structural transition at body temperature

G. M. Artmann, Laura T. Burns, +4 authors Christina Maggakis-Kelemen
European Biophysics Journal
2004

Previously we have shown that human red blood cells (RBCs) undergo a sudden change from blocking to passing through a 1.3±0.2-µm micropipette when applying an aspiration pressure of 2.3 kPa at a… (More)

Classification and Phylogenetic Analysis of the cAMP-Dependent Protein Kinase Regulatory Subunit Family

Jaume M. Canaves, Susan S. Taylor
Journal of Molecular Evolution
2002

The members of the PKA regulatory subunit family (PKA-R family) were analyzed by multiple sequence alignment and clustering based on phylogenetic tree construction. According to the phylogenetic… (More)

Domain organization of D-AKAP2 revealed by enhanced deuterium exchange-mass spectrometry (DXMS).

Yoshitomo Hamuro, Lora L Burns, Jaume M. Canaves, Ross C Hoffman, Susan Taylor, Virgil I Woods
Journal of molecular biology
2002

Dual specific A-kinase anchoring protein 2 (D-AKAP2) is a scaffold protein that coordinates cAMP-mediated signaling complexes by binding to type I and type II protein kinase A (PKA). While… (More)

Protein biophysical properties that correlate with crystallization success in Thermotoga maritima: maximum clustering strategy for structural genomics.

Jaume M. Canaves, Rebecca Page, Ian A. Wilson, Raymond C. Stevens
Journal of molecular biology
2004

Cost and time reduction are two of the driving forces in the development of new strategies for protein crystallization and subsequent structure determination. Here, we report the analysis of the… (More)

Functional analysis of substrate and cofactor complex structures of a thymidylate synthase-complementing protein.

Irimpan I Mathews, A. Deacon, +4 authors Peter Kuhn
Structure
2003

Like thymidylate synthase (TS) in eukaryotes, the thymidylate synthase-complementing proteins (TSCPs) are mandatory for cell survival of many prokaryotes in the absence of external sources of… (More)

Predicted role for the archease protein family based on structural and sequence analysis of TM1083 and MTH1598, two proteins structurally characterized through structural genomics efforts.

Jaume M. Canaves
Proteins
2004

Recently, the structures of two proteins belonging to the archease family, TM1083 from Thermotoga maritima and MTH1598 from Methanobacterium thermoautotrophicum, have been solved independently by two… (More)

Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline.

Scott A. Lesley, Peter Kuhn, +25 authors Raymond C. Stevens
Proceedings of the National Academy of Sciences…
2002

Structural genomics is emerging as a principal approach to define protein structure-function relationships. To apply this approach on a genomic scale, novel methods and technologies must be developed… (More)

Amino acid variant in the kinase binding domain of dual-specific A kinase-anchoring protein 2: a disease susceptibility polymorphism.

Stefan Kammerer, Lora L Burns-Hamuro, +8 authors Andreas Braun
Proceedings of the National Academy of Sciences…
2003

The focus of human genetics in recent years has shifted toward identifying genes that are involved in the development of common diseases such as cancer, diabetes, cardiovascular diseases, and… (More)

Crystal structure of a glycerate kinase (TM1585) from Thermotoga maritima at 2.70 A resolution reveals a new fold.

Robert Schwarzenbacher, Daniel McMullan, +25 authors Ian A. Wilson
Proteins
2006

Filter Results:

Publication Year

Publication Type

Co-author

Journals and Conferences

Brain Region

Organism