Learn More
The modeling, simulation, and experimental verification of several MEMS devices are presented. Simulated results include 3D mode analysis, residual stress effects, thermal expansion, nonlinear deflections, time-varying electrostatic forces, process sensitivities, induced currents, and the transient performance in accelerated reference frames. To simulate(More)
  • J V Clark
  • 1970
A 27 year old man had attacks of violence for three years before he died in 1945. Necropsy revealed multiple cavernous angiomata of the brain. This man's daughter died in 1969 at the age of 28 years after a year of intermittent headaches. Necropsy showed a large cavernous angioma in the right temporal lobe. Until now the literature has contained only scanty(More)
Three women dying from hepatic carcinoma during pregnancy are presented. One of these women with a hepatocellular carcinoma and alpha fetoprotein in the serum and antibody to hepatitis B antigen. A fourth patient died 2 months post partum with a cholangiocarcinoma. A false positive pregnancy test suggested that she had metastatic choriocarcinoma in the(More)
Early full-term pregnancy is one of the most effective natural protections against breast cancer. To investigate this effect, we have characterized the global gene expression and epigenetic profiles of multiple cell types from normal breast tissue of nulliparous and parous women and carriers of BRCA1 or BRCA2 mutations. We found significant differences in(More)
DNA electroporation has been demonstrated in preclinical models to be a promising strategy to improve cancer immunity, especially when combined with other genetic vaccines in heterologous prime-boost protocols. We report the results of 2 multicenter phase 1 trials involving adult cancer patients (n=33) with stage II-IV disease. Patients were vaccinated with(More)
SUGAR is a nodal analysis package for 3D MEMS simulation that owes its heritage and its name to the SPICE family of circuit simulation. SUGAR has undergone the stage of proof-of-concept which showed that nodal analysis was in fact just as accurate and much faster than nite element simulation on many MEMS problems. The upcoming major release of SUGAR is(More)
In this paper, we report several advances in the Sugar2.0 MEMS system simulation package, including reduced-order modeling techniques, simple hierarchical description of complex structures, synthesis tools, a variety of models, and a web-based interface. Examples include the modeling of a torsional micromirror with lateral actuators compared to experiment,(More)