Jason T. Stevens

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Many globular and natively disordered proteins can convert into amyloid fibrils. These fibrils are associated with numerous pathologies as well as with normal cellular functions, and frequently form during protein denaturation. Inhibitors of pathological amyloid fibril formation could be useful in the development of therapeutics, provided that the(More)
Many globular and natively disordered proteins can convert into amyloid fibers. These fibers are associated with numerous pathologies 1 as well as with normal cellular functions 2,3 , and frequently form during protein denaturation 4,5. Inhibitors of pathological amyloid fibers could serve as leads for therapeutics, provided the inhibitors were specific(More)
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