Jason Reilly

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The NSF TeraGrid project has designed and constructed a federated integrated information service (IIS) to serve its capability publishing and discovery needs. This service has also proven helpful in automating TeraGrid's operational activities. We describe the requirements that motivated this work; IIS's system architecture, information architecture, and(More)
Genomics research presents technical, computational, and analytical challenges that are well recognized. Less recognized are the complex sociological, psychological, cultural, and political challenges that arise when genomics research takes place within a large, decentralized academic institution. In this paper, we describe a Service-Oriented Architecture(More)
PurposeWe investigated the diagnostic and clinical performance of exome sequencing in fetuses with sonographic abnormalities with normal karyotype and microarray and, in some cases, normal gene-specific sequencing.MethodsExome sequencing was performed on DNA from 15 anomalous fetuses and from the peripheral blood of their parents. Parents provided consent(More)
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