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- Jason N. Bazil, Gregery T. Buzzard, Ann E. Rundell
- PLoS Computational Biology
- 2010
Mathematical models of mitochondrial bioenergetics provide powerful analytical tools to help interpret experimental data and facilitate experimental design for elucidating the supporting biochemical… (More)
- Jason N. Bazil, Gregory T Buzzard, Ann E. Rundell
- Bulletin of mathematical biology
- 2012
Model-based experiment design specifies the data to be collected that will most effectively characterize the biological system under study. Existing model-based design of experiment algorithms have… (More)
- Jason N. Bazil, Feng Qi, Daniel A. Beard
- Integrative biology : quantitative biosciences…
- 2011
Dynamic biological systems, such as gene regulatory networks (GRNs) and protein signaling networks, are often represented as systems of ordinary differential equations. Such equations can be utilized… (More)
- Jason N. Bazil, Christoph A Blomeyer, Ranjan Kumar Pradhan, Amadou K.S. Camara, Ranjan K. Dash
- Journal of bioenergetics and biomembranes
- 2013
Under high Ca(2+) load conditions, Ca(2+) concentrations in the extra-mitochondrial and mitochondrial compartments do not display reciprocal dynamics. This is due to a paradoxical increase in the… (More)
Catalytic Coupling of Oxidative Phosphorylation, ATP Demand, and Reactive Oxygen Species Generation.
- Jason N. Bazil, Daniel A. Beard, K. C. Vinnakota
- Biophysical journal
- 2016
Competing models of mitochondrial energy metabolism in the heart are highly disputed. In addition, the mechanisms of reactive oxygen species (ROS) production and scavenging are not well understood.… (More)
- Shivendra Gajraj Tewari, Ranjan K. Dash, Daniel A. Beard, Jason N. Bazil
- Biophysical journal
- 2012
Mitochondrial adenine nucleotide (AdN) content is regulated through the Ca(2+)-activated, electroneutral ATP-Mg/P(i) carrier (APC). The APC is a protein in the mitochondrial carrier super family that… (More)
- Christoph A Blomeyer, Jason N. Bazil, David F. Stowe, Ranjan Kumar Pradhan, Ranjan K. Dash, Amadou K.S. Camara
- Journal of bioenergetics and biomembranes
- 2013
In cardiac mitochondria, matrix free Ca(2+) ([Ca(2+)]m) is primarily regulated by Ca(2+) uptake and release via the Ca(2+) uniporter (CU) and Na(+)/Ca(2+) exchanger (NCE) as well as by Ca(2+)… (More)
- Rudrabhatla Sairam, Christopher Wilber, +8 authors Susan L. Goldman
- In Vitro Cellular & Developmental Biology - Plant
- 2007
A protocol for high-frequency callus, somatic embryogenesis, and plant regeneration for Tripsacum is described. Plants were regenerated from complete shoot meristems (3–4 mm) via organogenesis and… (More)
- Jason N. Bazil, Karl Stamm, +4 authors Daniel A. Beard
- PloS one
- 2014
Cardiac development is a complex, multiscale process encompassing cell fate adoption, differentiation and morphogenesis. To elucidate pathways underlying this process, a recently developed algorithm… (More)
- Michael A. Moxley, Daniel A. Beard, Jason N. Bazil
- Biophysical journal
- 2014
Dihydrolipoamide dehydrogenase is a flavoenzyme that reversibly catalyzes the oxidation of reduced lipoyl substrates with the reduction of NAD(+) to NADH. In vivo, the dihydrolipoamide dehydrogenase… (More)