Jason M. Park

Learn More
BACKGROUND Controversy exists whether young patients diagnosed with colorectal cancer have a poorer prognosis. Although younger patients are more likely to have certain poor prognostic factors, prior studies have shown mixed results in terms of overall prognosis, which may be due to lack of adjustment for confounding factors. The primary objective of our(More)
The cyanide dihydratases from Bacillus pumilus and Pseudomonas stutzeri share high amino acid sequence similarity throughout except for their highly divergent C-termini. However, deletion or exchange of the C-termini had different effects upon each enzyme. Here we extended previous studies and investigated how the C-terminus affects the activity and(More)
BACKGROUND The Canadian province of Manitoba covers a large geographical area but only has one major urban center, Winnipeg. We sought to determine if regional differences existed in the quality of colorectal cancer care in a publicly funded health care system. METHODS This was a population-based historical cohort analysis of the treatment and outcomes of(More)
Nitrilases are of significant interest both due to their potential for industrial production of valuable products as well as degradation of hazardous nitrile-containing wastes. All known functional members of the nitrilase superfamily have an underlying dimer structure. The true nitrilases expand upon this basic dimer and form large spiral or helical(More)
Enhanced pond systems (EPS) are an effective and economic upgrade option for conventional wastewater treatment ponds providing improved natural disinfection and nutrient removal. Moreover, wastewater nutrients are recovered as harvested algal biomass for beneficial use as fertiliser, feed or biofuel feedstock. Low-cost construction and operation are crucial(More)
  • 1