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Polycyclic aromatic hydrocarbons (PAHs) are an important class of toxic pollutants released by fossil fuel combustion. Other pollutants include metals and particulate matter. PAH-DNA adducts, or benzo[a]pyrene (BaP) adducts as their proxy, provide a chemical-specific measure of individual biologically effective doses that have been associated with increased(More)
BACKGROUND Environmental pollutants such as polycyclic aromatic hydrocarbons (PAHs), lead, and mercury are released by combustion of coal and other fossil fuels. OBJECTIVES In the present study we evaluated the association between prenatal exposure to these pollutants and child development measured by the Gesell Developmental Schedules at 2 years of age.(More)
BACKGROUND Coffee is an important source of antioxidants, and consumption of this beverage is associated with many health conditions and a lower mortality risk. However, no study, to our knowledge, has examined whether varying coffee or caffeine consumption levels are associated with telomere length, a biomarker of aging whose shortening can be accelerated(More)
Sleep plays a pivotal role in the quality of life, and sleep posture is related to many medical conditions such as sleep apnea. In this paper, we design a dense pressure-sensitive bedsheet for sleep posture monitoring. In contrast to existing techniques, our bedsheet system offers a completely unobtrusive method using comfortable textile sensors. Based on(More)
Detecting human activity independent of intensity is essential in many applications, primarily in calculating metabolic equivalent rates (MET) and extracting human context awareness from on-body inertial sensors. Many classifiers that train on an activity at a subset of intensity levels fail to classify the same activity at other intensity levels. This(More)
Remote health monitoring (RHM) can help save the cost burden of unhealthy lifestyles. Of increased popularity is the use of smartphones to collect data, measure physical activity, and provide coaching and feedback to users. One challenge with this method is to improve adherence to prescribed medical regimens. In this paper we present a new battery(More)
Sonic Hedgehog (Shh)-deficient mice have a severe lung branching defect. Recent studies have shown that hedgehog signaling is involved in vascular development and it is possible that the diminished airway branching in Shh-deficient mice is due to abnormal pulmonary vasculature formation. Therefore, we investigated the role of Shh in pulmonary vascular(More)
— Sleep constitutes a big portion of our lives and is a major part of health and well-being. Monitoring the quality of sleep can aid in the medical diagnosis of a variety of sleep and psychiatric disorders and can serve as an indication of several chronic diseases. Sleep stage analysis plays a pivotal role in the evaluation of the quality of sleep and is a(More)
Gait analysis is an important medical diagnostic process and has many applications in rehabilitation, therapy and exercise training. However, standard human gait analysis has to be performed in a specific gait lab and operated by a medical professional. This traditional method increases the examination cost and decreases the accuracy of the natural gait(More)
Recent investigations have suggested an active role for endothelial cells in organ development, including the lung. Herein, we investigated some of the molecular mechanisms underlying normal pulmonary vascular development and their influence on epithelial branching morphogenesis. Because the lung in utero develops in a relative hypoxic environment, we first(More)