Jason Freeman

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The world's oceans contain a complex mixture of micro-organisms that are for the most part, uncharacterized both genetically and biochemically. We report here a metagenomic study of the marine planktonic microbiota in which surface (mostly marine) water samples were analyzed as part of the Sorcerer II Global Ocean Sampling expedition. These samples,(More)
Spinocerebellar ataxia (SCA) 17 is a dominant, progressive, neurodegenerative disorder. The disease is caused by a triplet repeat expansion mutation within TATA-binding protein (TBP). Ataxia, dementia, parkinsonism and dystonia are common features. We have previously shown in several pedigrees that SCA-2 and SCA-3 can cause both parkinsonism and typical(More)
Are "generalized" seizures truly generalized? Generalized tonic-clonic seizures are classified as either secondarily generalized with local onset or primarily generalized, without known focal onset. In both types of generalized seizures widespread regions of the nervous system engage in abnormally synchronous and high-frequency neuronal firing. However,(More)
EarSketch is a novel approach to teaching computer science concepts via algorithmic music composition and remixing in the context of a digital audio workstation paradigm. This project includes a Python/Javascript coding environment, a digital audio workstation view, an audio loop browser, a social sharing site and an integrated curriculum. EarSketch is(More)
EarSketch (http://earsketch.gatech.edu) is an integrated curriculum, software toolset, audio loop library, and social sharing site that teaches computing principles through digital music composition and remixing. Attendees will learn to code in Python and/or JavaScript to place audio clips, create rhythms, and add and control effects within a multi-track(More)
Cigarette smoking enhances oxidative stress and airway inflammation in asthma, the mechanisms of which are largely unknown. Myeloid-derived regulatory cells (MDRC) are free radical producing immature myeloid cells with immunoregulatory properties that have recently been demonstrated as critical regulators of allergic airway inflammation. NO (nitric(More)