Jason E. Ferrara

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Experimental and model studies were performed to measure the electrocardiographic surface Laplacian using a rectangular finite difference approximation. The experimental approach used ten normal subjects with two sites on the torso. Electrode spacing was 2 cm. The surface Laplacian is theoretically independent of rotation of the electrode array. The data(More)
A Monte Carlo method is given to compute the binding affinity of a ligand to a protein. The method involves extending configuration space by a discrete variable indicating whether the ligand is bound to the protein and a special Monte Carlo move, which allows transitions between the unbound and bound states. Provided that an accurate protein structure is(More)
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