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The bioequivalence problem is of practical importance because the approval of most generic drugs in the United States and the European Community (EC) requires the establishment of bioequivalenceâ€¦ (More)

Not all simultaneous inferences need multiplicity adjustment. If the sequence of individual inferences is predeened, and failure to achieve the desired inference at any step renders subsequentâ€¦ (More)

- Jason C. Hsu, Barry L. Nelson
- Winter Simulation Conference
- 1987

Some new quantile estimators that employ a control variate are introduced. The properties of these estimators do not depend on the usual assumption of joint normality between the random variable ofâ€¦ (More)

- Youlan Rao, Yoonkyung Lee, +4 authors John P. Hagan
- Statistical applications in genetics andâ€¦
- 2008

Normalization of expression levels applied to microarray data can help in reducing measurement error. Different methods, including cyclic loess, quantile normalization and median or meanâ€¦ (More)

- Karla Zadnik, Donald O. Mutti, +6 authors Melvin L. Moeschberger
- Investigative ophthalmology & visual science
- 1999

PURPOSE
The purpose of this study was to identify reliable predictors of the onset of juvenile myopia.
METHODS
The data from 554 children enrolled in the Orinda Longitudinal Study of Myopia (OLSM)â€¦ (More)

We develop a real options model of R&D valuation, which takes into account the uncertainty in the quality of the research output, the time and cost to completion, and the market demand for the R&Dâ€¦ (More)

- Jason C. Hsu
- 2004

The accuracy of a medical diagnostic tool depends on its specificity, the probability that it classifies a normal person as normal, and its sensitivity, the probability that it classifies a diseasedâ€¦ (More)

- Jason C. Hsu, Barry L. Nelson
- Winter Simulation Conference
- 1988

Multiple comparisons with the best, which is applicable to single-stage experiments, is introduced as a method for choosing the best of a finite number of system designs. Examples are given.

- K S Fritsch, Jason C. Hsu
- Biometrics
- 1999

Did the biodiversity of dinosaurs decline, or did it remain more or less constant before their mass extinction 65 million years ago? Sheehan et al. (1991, Science, 835-839) reported that theâ€¦ (More)

- Yifan Huang, Haiyan Xu, Violeta Calian, Jason C. Hsu
- Bioinformatics
- 2006

UNLABELLED
Permutation test is a popular technique for testing a hypothesis of no effect, when the distribution of the test statistic is unknown. To test the equality of two means, a permutation testâ€¦ (More)