Jason A. Roy

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Global epidemiology of pediatric severe sepsis: the sepsis prevalence, outcomes, and therapies study.

Scott L. Weiss, Julie C. Fitzgerald, +9 authors N. P. J. Thomas
American journal of respiratory and critical care…
2015

RATIONALE Limited data exist about the international burden of severe sepsis in critically ill children. OBJECTIVES To characterize the global prevalence, therapies, and outcomes of severe sepsis… (More)

Standards should be applied in the prevention and handling of missing data for patient-centered outcomes research: a systematic review and expert consensus.

Tianjing Li, Susan Hutfless, +6 authors Kay Dickersin
Journal of clinical epidemiology
2014

OBJECTIVES To recommend methodological standards in the prevention and handling of missing data for primary patient-centered outcomes research (PCOR). STUDY DESIGN AND SETTING We searched National… (More)

Tom Ten Have's contributions to causal inference and biostatistics: review and future research directions.

Dylan S. Small, Marshall M. Joffe, Kevin Gerard Lynch, Jason A. Roy, A Russell Localio
Statistics in medicine
2014

Tom Ten Have made many contributions to causal inference and biostatistics before his untimely death. This paper reviews Tom's contributions and discusses potential related future research… (More)

Disparities in Absolute Denial of Modern Hepatitis C Therapy by Type of Insurance.

Vincent Lo Re, C. D. Raghavendra Gowda, +11 authors Jay R. Kostman
Clinical gastroenterology and hepatology : the…
2016

BACKGROUND & AIMS The high costs of direct-acting antiviral (DAA) agents to treat chronic hepatitis C virus (HCV) infection have resulted in denials of treatment, but it is not clear whether… (More)

Methods for Estimating Kidney Disease Stage Transition Probabilities Using Electronic Medical Records

Lola Luo, Dylan Small, Walter F. Stewart, Jason A. Roy
EGEMS
2013

Chronic diseases are often described by stages of severity. Clinical decisions about what to do are influenced by the stage, whether a patient is progressing, and the rate of progression. For chronic… (More)

Statistical Methods for Cohort Studies of CKD: Survival Analysis in the Setting of Competing Risks.

Jesse Yenchih Hsu, Jason A. Roy, +9 authors Harold I. Feldman
Clinical journal of the American Society of…
2017

Survival analysis is commonly used to evaluate factors associated with time to an event of interest (e.g., ESRD, cardiovascular disease, and mortality) among CKD populations. Time to the event of… (More)

Use of demographic and pharmacy data to identify patients included within both the Clinical Practice Research Datalink (CPRD) and The Health Improvement Network (THIN).

Dena M. Carbonari, M. Elle Saine, +10 authors Vincent Lo Re
Pharmacoepidemiology and drug safety
2015

PURPOSE Pharmacoepidemiology researchers often utilize data from two UK electronic medical record databases, the Clinical Practice Research Datalink (CPRD) and The Health Improvement Network (THIN),… (More)

Statistical Methods for Recurrent Event Analysis in Cohort Studies of CKD.

Wei Yang, Christopher Jepson, +7 authors Harold I. Feldman
Clinical journal of the American Society of…
2017

Cardiovascular events, such as hospitalizations because of congestive heart failure, often occur repeatedly in patients with CKD. Many studies focus on analyses of the first occurrence of these… (More)

Postauthorization safety study of the DPP-4 inhibitor saxagliptin: a large-scale multinational family of cohort studies of five outcomes

Vincent Lo Re, Dena M. Carbonari, +16 authors Brian L. Strom
BMJ open diabetes research & care
2017

OBJECTIVE To evaluate the risk of serious adverse events among patients with type 2 diabetes mellitus initiating saxagliptin compared with oral antidiabetic drugs (OADs) in classes other than… (More)

A framework for Bayesian nonparametric inference for causal effects of mediation.

Chanmin Kim, Michael J. Daniels, Bess H. Marcus, Jason A. Roy
Biometrics
2017

We propose a Bayesian non-parametric (BNP) framework for estimating causal effects of mediation, the natural direct, and indirect, effects. The strategy is to do this in two parts. Part 1 is a… (More)

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