Jason A Goldsmith

Learn More
Postprandial hypoglycaemia following gastric bypass for obesity is considered a late manifestation of the dumping syndrome and can usually be managed with dietary modification. We investigated three patients with severe postprandial hypoglycaemia and hyperinsulinaemia unresponsive to diet, octreotide and diazoxide with the aim of elucidating the(More)
OBJECTIVE To assess the accuracy of classification of narrow anterior chamber (AC) angles using quantitative imaging by optical coherence tomography (OCT) and ultrasound biomicroscopy (UBM). DESIGN Observational comparative study. METHODS A high-speed (4000 axial scans/s) anterior segment OCT prototype was developed using a 1.3-microm light source.(More)
Exfoliation glaucoma (XFG) is the commonest identifiable cause of secondary open-angle glaucoma worldwide, characterized by the deposition of fibrillar proteins in the anterior segment of the eye. We investigated LOXL1 gene variants previously identified to confer susceptibility to XFG in a Utah Caucasian cohort. After a standard eye examination protocol we(More)
Inhaled nitric oxide (NO) decreases pulmonary arterial pressure (Ppa) and improves oxygenation in the adult respiratory distress syndrome. Endogenous NO can modulate the development of acute tissue injury. We investigated the effects of inhaled NO and of inhibition of endogenous NO synthase in oxidant-induced acute lung injury in the isolated(More)
Nonpenetrating glaucoma surgery continues to evolve and improve. New technical refinements and increased experience among its practitioners have led to improved efficacy and longer duration of filter survival. These refinements include the use of intraoperative and postoperative antimetabolites, adjunctive space-maintaining devices, and postoperative(More)
OBJECTIVE To measure anterior chamber (AC) width and other dimensions relevant to the sizing of phakic intraocular lenses (IOLs) with a high-speed optical coherence tomography (OCT) system. DESIGN Cross-sectional observational study. PARTICIPANTS Both eyes of 20 normal volunteers. METHODS A novel high-speed (4000 axial scans/second) OCT prototype was(More)
PURPOSE To report a case of bilateral non-pupillary block angle closure glaucoma after Visian Implantable Collamer Lens (ICL, STAAR Surgical) surgery. METHODS A 35-year-old woman with high myopia, white-to-white measurements of 11.8 mm in the right eye and 11.9 mm in the left eye, and anterior chamber depths >3 mm in both eyes underwent simultaneous(More)
OBJECTIVE To examine the associations of provider-patient communication, glaucoma medication adherence self-efficacy, and outcome expectations with glaucoma medication adherence. DESIGN Prospective, observational cohort study. PARTICIPANTS Two hundred seventy-nine patients with glaucoma who were newly prescribed or taking glaucoma medications were(More)
PURPOSE To report and compare the results of trabeculectomy with mitomycin C (MMC) and Ahmed valve implantation in the management of uveitic glaucoma. PATIENTS AND METHODS The records of 41 eyes of 29 patients who underwent trabeculectomy with MMC or Ahmed valve implantation for uveitic glaucoma were retrospectively reviewed. Seventeen eyes underwent(More)
BACKGROUND Many factors influence glaucoma medication adherence. A better understanding of the relationships between health literacy, depressive symptoms, and patient-reported problems in using glaucoma medications may reveal opportunities for intervention that could improve patients' clinical outcomes. OBJECTIVE To examine the relationship between(More)