Jason A Goebel

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OBJECTIVE To review current clinical data regarding the pharmacologic actions of ruboxistaurin (LY333531) mesylate, an inhibitor of protein kinase C (PKC) beta, and its role to potentially reduce the development and/or the progression of diabetic microvascular complications. DATA SOURCES Primary literature was obtained via a MEDLINE search (1966-August(More)
Chronic heart failure poses an enormous health care burden to the United States and other developed countries. Acute decompensated heart failure (ADHF) accounts for nearly half of the morbidity and expense of treating this disease. Most patients presenting with ADHF have symptomatic vascular congestion. Diuretics, especially loop diuretics, are the primary(More)
Es werden die diagnostischen Kriterien für M. Menière beschrieben, die vom Klassifikationskomitee der Bárány-Gesellschaft, der Japanischen Gesellschaft für Gleichgewichtsforschung, der Europäischen Akademie für Otologie und Neurootologie (EAONO), dem Komitee für Gleichgewichtsstörungen der Amerikanischen Akademie für Otolaryngologie, Kopf- und(More)
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