Jason A. Dominitz

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Esophageal cancer is currently the fastest growing cancer in the United States. To help combat the recent rise in morbidity, our laboratory has developed a low-cost tethered capsule endoscope system (TCE) aimed at improving early detection of esophageal cancer. The TCE contains a resonant fiberoptic laser scanner (1.6 mm O.D.) which fits into 6.4-mm(More)
This is one of a series of statements discussing the use of GI endoscopy in common clinical situations. The Standards of Practice Committee of the American Society for Gastrointestinal Endoscopy prepared this text. In preparing this guideline, a search of the medical literature was performed by using PubMed. Additional references were obtained from the(More)
OBJECTIVE Valproic acid is frequently not recommended for patients with hepatic dysfunction. The authors evaluated the association between hepatitis C and alanine aminotransferase (ALT) values during valproic acid treatment. METHOD ALT changes in 564 individuals beginning valproic acid treatment were examined. Changes among those with positive hepatitis C(More)
The Multi-Society Task Force, in collaboration with invited experts, developed guidelines to assist health care providers with the appropriate provision of genetic testing and management of patients at risk for and affected with Lynch syndrome as follows: provides a colorectal cancer risk assessment tool to screen individuals in the office or endoscopy(More)
This is one of a series of statements discussing the use of GI endoscopy in common clinical situations. The Standards of Practice Committee of the American Society for Gastrointestinal Endoscopy (ASGE) prepared this text. This guideline combines and updates 2 previously issued guidelines, ''Guideline on the management of antithrom-botic and antiplatelet(More)
Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the United States. 1 Colonoscopy can prevent CRC by the detection and removal of precan-cerous lesions. In addition to CRC screening and surveillance , colonoscopy is used widely for the diagnostic evaluation of symptoms and other positive CRC screening tests. Regardless of(More)
Thirty-nine patients with hepatitis C viral infection on interferon-alpha (IFN-alpha) therapy were monitored weekly using the Beck Depression Inventory (BDI). Thirteen of thirty-nine patients (33%) developed IFN-alpha-induced major depressive disorder (MDD). During the course of IFN-alpha therapy, patients who became depressed were treated with citalopram,(More)
Algorithms for appropriate utilization of endoscopy are based on a critical review of the currently available data and expert consensus. Controlled clinical studies may in some cases be needed to clarify aspects of this statement, and revision may be necessary as new data appear. These algorithms are intended to serve as a guide for management of common(More)