Jarree Chaicharn

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STUDY OBJECTIVES To quantitatively assess autonomic cardiovascular control in normal young adults following exposure to repetitive acoustically-induced arousals from sleep. DESIGN Respiration, R-R interval (RRI) and noninvasive measurements of continuous arterial blood pressure were monitored in subjects during the transition from relaxed wakefulness to(More)
STUDY OBJECTIVES To quantitatively assess daytime autonomic cardiovascular control in pediatric subjects with and without obstructive sleep apnea syndrome (OSAS). DESIGN Respiration, R-R intervals, and noninvasive continuous blood pressure were monitored in awake subjects in the supine and standing postures, as well as during cold face stimulation. (More)
Adults with obstructive sleep apnea syndrome (OSAS) are known to have impaired autonomic function but the corresponding effects in children appear to be more subtle. Model-based analysis of the cardiovascular response to cold face test (CFT) was used to quantify daytime autonomic dysfunction. The increase in transfer gain between respiration and RRI was not(More)
IT IS NOW REASONABLY WELL ESTABLISHED THAT OBSTRUCTIVE SLEEP APNEA (OSA) CONSTITUTES AN INDEPENDENT RISK FACTOR FOR DAYTIME HYPERTENSION.1,2 The potential mechanisms that could link OSA to hypertension include chronic exposure to intermittent hypoxia, large intrathoracic pressure swings, and repetitive arousals from sleep occurring at the termination of(More)
A previous study found that the sympathoexcitatory cardiovascular effects of arousal are relatively long lasting. In this study, we examine (1) whether the cumulative effects of arousal can lead to significant changes in autonomic control and (2) how the frequency of arousals affect the magnitude of these effects. Ten healthy subjects were aroused from(More)
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