Jaroslav Weber

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The spatial distribution of cations was assayed qualitatively and quantitatively in tentacular nematocytes of Hydra vulgaris in a scanning transmission electron microscope by means of x-ray microanalysis performed on 100 nm thick freeze-dried cryosections. The matrix of undischarged cysts (stenoteles, desmonemes and isorhizas) was found to contain mainly(More)
The study of metabolic fuel provision and its regulation has reached an exciting stage where specific molecular events can be correlated with parameters of the organism's ecology. This paper examines substrate supply pathways from storage sites to locomotory muscle mitochondria and discusses ecological implications of the limits for maximal flux through(More)
Cronobacter sakazakii and C. malonaticus are opportunistic pathogens that cause infections in children and immunocompromised adults. In the present study, the antibacterial activity of 19 plant-derived compounds, 5 essential oils, and an extract of propolis were assessed against C. sakazakii and C. malonaticus. The effects of most of these antimicrobials(More)
A quantitative study of the life cycle ofSkrjabingylus nasicola was made. Before estimating the losses at each level of the cycle, we needed to know the location of the infectious larval stage in the paratenic host. We found that a significant number of L3 encapsulate in the anterior part of the paratenic host. The cephalic glandular zones, salivary and(More)
An X-ray spectral analysis (EDAX) of isolated undischarged nematocysts of various cnidarians (Hydrozoa, Scyphozoa, Anthozoa) revealed the presence of extremely high concentrations of divalent cations. InHydra nematocysts both Ca2+ (conc. 0.36 μmole/mg dry cysts) and Mg2+ (conc. 0.80 μmole/mg dry cysts) ions add up to a total in situ concentration of 0.5 to(More)
The autosomal dominant cerebellar ataxias have proved particularly difficult to classify due to the lack of phenotypic concordance both within and between families. Genetic heterogeneity has been established, and disease loci for spinal cerebellar ataxia have been assigned to chromosomes 6 (SCA1), 12 (SCA2) and 14 (Machado Joseph disease (MJD)). Genetic(More)
From the roots ofCroton flavens L., 3 highly irritant and tumor promoting Croton factorsF 1–F 3 and the corresponding 3 cryptic Croton factorsF′1–F′3 were isolated and characterized as novel esters of 16-hydroxy- and 4-deoxy-16-hydroxyphorbol, respectively. These findings suggest that tumor promoters of the phorbol ester type, ingested through the(More)
Sarcopenia is defined by loss of muscular mass, strength and quality that occur in elderly. Multiple factors underlie this process: low physical activity, low steroids hormones, increase of cytokines, loss of motoneurons, decrease of protein synthesis...However, the role of these factors is not yet well understood and consensual clinical definition and(More)
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