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Hippocampal pyramidal neurons (area CA1) in rats, 5, 10, 15, 24, 48 and 90 days old were studied by means of the Golgi-Cox impregnation. Using a video-computer microscope the development of dendritic arborisation was analysed and descriptive as well as quantitative data were obtained. During the suckling period (5 and 10 days) the basal dendrites, the main(More)
Fine structure of stratum moleculare and lacunosum of the hippocampal CA1 area was studied in rats 5, 10, 15, 24, 48 and 90 days old. By means of an electron microscope the detailed description of both layers as well as quantitative data about the development of neuropile were obtained. The density of dendrites per 1 mm3 decreased during the development.(More)
This study used an experimental early rehabilitation model combining an enriched environment, multisensory (visual, acoustic and olfactory) stimulation and motor training after traumatic brain injury (via fluid-percussion model) to simulate early multisensory rehabilitation. This therapy will be used by brain injured patients to improve neural plasticity(More)
BACKGROUND Cerebral ischemia induces a massive release of norepinephrine associated with neuronal death in the brain. It has been demonstrated that alpha2-adrenoceptor agonists decrease the release and turnover of noradrenaline, and this might prove advantageous in counteracting the neurodegeneration in ischemic brain. Therefore, in the present study, the(More)
The structure of pyramidal cells in the CA1 hippocampal region, impregnated by the Golgi-Cox method, was studied in adult rats which had been repeatedly exposed to aerogenic hypoxia from birth till the 17th day of life. The length of basal dendrite branches was the same in the experimental and control animals. The branches of apical dendrites were longer(More)
The authors compare the structure of the pyramidal neurones in the CA1 region of the hippocampus in rats repeatedly exposed to aerogenic hypoxia from birth to the age of 17 days and in control animals. In preparations from 18-day-old animals impregnated by the Colgi-Cox method the length of the dendrites and the density of the spines were quantitatively(More)
Goal-directed navigation is believed to be the combined product of idiothetic and allothetic orientation. Although both navigation systems require the hippocampal formation, it is probable that different circuits implement them. Examination of Long-Evans rats with dentate gyrus lesions induced by neonatal X-ray irradiation may show the dissociation of these(More)
Infant rats, together with the female, were exposed to a simulated altitude of 7,000 m every day from birth to the age of 17 days, excepting the 6th, 7th, 13th and 14th day. Animals were studied on the 18th day, 20 hours after the last exposure to hypoxia. Rats aged 12, 15 and 18 days acted as the controls. The number of myelinated axones of the corpus(More)
Evans blue was applied to 12 rats by way of intracarotid injection into the common carotid artery or internal carotid artery both with the blood-brain barrier intact and after its mannitol-induced osmotic opening. For each type of application, a histological picture of Evans blue propagation through the brain was obtained by means of fluorescence(More)