Jaroslav Doubek

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BACKGROUND/AIMS Critically ill patients especially who require mechanical ventilation or have coagulopathy are at increased risk for stress-related gastrointestinal hemorrhage. There are conflicting data on the efficacy and complication rates of various prophylactic regimens. METHODOLOGY Our single-center randomized, placebo-controlled study included 287(More)
Amphotericin B (AmB)-treated rats develop severe polyuria, polydypsia, impairment of renal concentrating ability, and morphologic signs of tubular damage. However, renal insufficiency develops quickly only in animals in which water intake is restricted to the median volume drunk by rats of the control group. Therefore, vigorous hydration seems crucial for(More)
BACKGROUND/AIMS Norepinephrine, but also dopamine and epinephrine are recommended as first line vasopressors in the treatment of septic shock. In some patients, septic shock deteriorates and becomes to be resistant to catecholamines. In this situation, addition of vasopressin or terlipressin can be advantageous. The aim of our pilot study was to evaluate(More)
BACKGROUND/AIMS The pathogenesis of acute stress-related hemorrhage in critically ill polytraumatized patients is uncertain and any role of Helicobacter pylori infection is unknown. The aim of our study was to evaluate the relationship between Helicobacter pylori serological status of patients developing stress-related bleeding and those with no appearance(More)
A 15-month-old dachshund was presented for examination because of a cough. Thoracic radiographs revealed the presence of a mass in the upper mediastinum. A diagnosis of gammadelta T-cell lymphoma was made by biopsy and flow cytometry analysis. The dog was treated with chemotherapy and remains asymptomatic after 24 months.
Unicellular freshwater microalgae of the genus Chlorella are characterised by a relative ease of cultivation, high productivity and high content of proteins and other valuable components. However, the alga is too expensive to use widely as a protein supplement in animal feed. Nevertheless, in many experiments, it was found that even a very low, economically(More)
BACKGROUND AND AIM Amphotericin B (AmB) desoxycholate remains as one of the most efficacious agents currently available for the treatment of systemic fungal infections; however, amphotericin B colloidal dispersion (ABCD) has been developed because of AmB desoxycholate nephrotoxicity. The goal of our study was to compare the effect of administration of AmB(More)
Dehorning adult cattle is a surgical procedure causing distress of varying intensities that can be reflected in behavioural changes and alterations in plasma cortisol levels. Stress responses during the dehorning process were evaluated in 18 Red Pied cows. The cows were divided into 3 groups of six and kept in tie-stall housing. Those in the first group(More)
The effect of age and sex on blood acid-base and plasma electrolyte values was determined in venous blood samples from 45 clinically healthy ostriches (Struthio camelus) from 26 days to 6 years of age. Animals were divided by age into four groups and the group of adults was divided by sex into two subgroups. Blood samples were collected without sedation.(More)