Jarosław Kalinka

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OBJECTIVE Recent studies suggest that preterm delivery might be conditioned genetically. The main aim of this study was to examine the relationship between spontaneous preterm delivery (PTD) and the carriage of polymorphic genes that code the following cytokines: interleukin-1beta [IL1beta (+3953C>T)], interleukin-6 promoter [IL6 (-174G>C)], tumour necrosis(More)
PROBLEM The therapeutic value of progestogens in threatened abortion is still under debate. In the presence of sufficient progesterone levels during pregnancy, lymphocytes synthesize a mediator [progesterone-induced blocking factor (PIBF)] that is anti-abortive in mice. The aim of this study was to evaluate the effect of dydrogesterone on pregnancy outcome(More)
PROBLEM The role of increased Th1 cytokine expression in pregnancy failure has been questioned recently. The therapeutic value of progestogens in threatened abortion (TA) is still debated. The aim of this prospective study was to compare serum cytokine [tumor necrosis factor (TNF)-alpha, interleukin (IL)-12 and IL-10] concentrations in women with TA to(More)
AIM While there are sufficient data regarding the negative effect of exposure to the constituents of tobacco smoke on newborn infants' birth weights, it is still unclear whether this effect may originate in early pregnancy. The aim of the present study was to evaluate the impact of exposure to tobacco smoke components in early pregnancy (20-24 weeks) on(More)
1. The present investigation was undertaken to evaluate the effect of environmental tobacco smoke (ETS) on the risk of preterm delivery (PD) and small-for-gestational age (SGA) infants in a female non-smoking population of central Poland. 2. The study group were 1751 women classified as non-smokers in the comprehensive project on 'Socio-economic and(More)
BACKGROUND Unemployment is one of the consequences of the ongoing transformation of the Polish economy. The main objective of the present study was to investigate the relationship between women's employment status and preterm delivery (PD) and/or small-for-gestational-age (SGA) infants, in Central Poland during the socio-economic transition. METHODS The(More)
The aim of this prospective cohort study was to evaluate the impact of tobacco smoke exposure, measured by maternal serum concentration of cotinine, on fetal midgestation biometric parameters and umbilical artery (UA) qualitative blood flow indices. The study population consisted of 114 healthy women in 20 to 24 weeks gestation who were recruited from the(More)
The main goal of the project was to estimate the effect of environmental tobacco smoke (ETS) exposure on the birthweight. In a cohort of 196 pregnant women in 20-24 week of pregnancy the serum and urine cotinine levels were determined. The cohort included randomly selected pregnant patients of a maternity units in Lodz, Poland. To assess a 24 h exposure to(More)
The aim of the paper was to evaluate the association between preconceptional and prenatal exposure to tobacco smoke and the risk of all cancers combined and separately, for brain tumors, leukemias, lymphomas and other childhood cancers. We conducted systematic search of the literature using PUBMED, MEDLINE and EBSCO database to identify all publications(More)
PROBLEM The main aim of this study was to investigate the relationship between selected proinflammatory cytokines [interleukin IL-1 alpha (IL-1alpha), IL-1 beta (IL-1beta), IL-6 and IL-8] concentrations in cervicovaginal fluid, as measured in midgestation, and the risk of subsequent preterm delivery. METHOD OF STUDY Cervicovaginal fluids were obtained(More)