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OBJECTIVES Axonal damage in multiple sclerosis (MS) may be reflected by antibodies against axon-specific proteins - the light subunit of neurofilaments (NFL). MATERIALS AND METHODS The serum and cerebrospinal fluid obtained from 58 MS patients, 24 normal controls (CN), 49 control patients with miscellaneous diseases (CD) and 31 patients with(More)
BACKGROUND AND PURPOSE Coherence changes can reflect the pathophysiological processes involved in human ageing. We conducted a retrospective population study that sought to analyze the age-related changes in EEG coherence in a group of 17,722 healthy professional drivers. MATERIALS AND METHODS The EEGs were obtained using a standard 10-20 electrode(More)
BACKGROUND Proteinase-activated receptor 2 (PAR-2) has been shown to promote both neurotoxic and neuroprotective effects. Similarly, other routinely used nonspecific markers of neuronal damage can be found in cerebrospinal fluid (CSF) and can be used as biomarkers for different neurodegenerative disorders. METHODS Using enzyme-linked immunosorbent assays(More)
BACKGROUND Symptoms of anxiety and depression are common among family members of ICU patients and are culturally dependent. The aim of the study was to assess the prevalence of symptoms of anxiety and depression and associated factors in family members of ICU patients in two Central European countries. METHODS We conducted a prospective multicenter study(More)
Age-related changes in the EEG energy and spectral composition were examined in 17,722 healthy subjects (truck drivers), 20 to 70 years old. Linear correlations between age vs global EEG energy and spectral powers (SPs) of EEG frequency ranges were estimated by linear regression analysis. Significant dependences of the global EEG energy and SPs of all EEG(More)
At present vision prosthesis proposes transmission of only a limited amount of visual information. Cutaneous receptor field may serve as a information channel. It has similar information-processing ability as retina. Lower information capacity of the skin may be compensated by wavelet transform image compression. Advances in microtechnology have facilitated(More)