Jarkko Heiskanen

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The most common means of mobilizing autologous stem cells is G-CSF alone or combined with cyclophosphamide (CY) to obtain sufficient CD34+ cells for one to two transplants. There are few prospective, randomized studies investigating mobilization regimens in multiple myeloma (MM), especially after lenalidomide-based induction. We designed this prospective,(More)
Some reports suggest that blood stem cell mobilization is difficult in a proportion of patients with CLL. We evaluated this issue in a large cohort of CLL patients. One hundred and twenty-eight patients with CLL underwent blood stem cell mobilization during 1995–2005 in Finland. Ninety-five percent of the patients had received fludarabine. The most common(More)
OBJECTIVE Aortic sinus dilatation can lead to aortic valve regurgitation or even aortic dissection. Our objective was to examine the association between body surface area (BSA) measures from childhood to middle age and aortic sinus diameter in middle age. Understanding the relation of these two clarifies how aortic size is normally determined. METHODS(More)
OBJECTIVE To analyse how treatment of patients with rheumatoid arthritis (RA) influenced the duration of the disease before the first large joint surgery, arthrodesis or arthroplasty, in two patient cohorts 10 years apart. METHODS Data on patients with RA having an arthrodesis or arthroplasty of a large joint from 1990 to 1992 and from 2000 to 2002 and(More)
Veno-occlusive disease of the liver (VOD), also called sinusoidal obstruction syndrome, is a potentially serious complication of hematopoietic stem cell transplantation which is thought to be mainly caused by the conditioning treatment preceding the transplantation. The reported incidences of VOD have varied widely. In recent reviews the present incidence(More)
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