Jari T. Kiuru

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We present FiD (Fragment iDentificator), a software tool for the structural identification of product ions produced with tandem mass spectrometric measurement of low molecular weight organic compounds. Tandem mass spectrometry (MS/MS) has proven to be an indispensable tool in modern, cell-wide metabolomics and fluxomics studies. In such studies, the(More)
Saccharomyces cerevisiae CEN.PK113-1A was grown in glucose-limited chemostat culture with 0%, 0.5%, 1.0%, 2.8% or 20.9% O2 in the inlet gas (D=0.10 h(-1), pH 5, 30 degrees C) to determine the effects of oxygen on 17 metabolites and 69 genes related to central carbon metabolism. The concentrations of tricarboxylic acid cycle (TCA) metabolites and all(More)
Raimo A. Ketola a,b,∗, Jari T. Kiuru a, Virpi Tarkiainen a, Juha T. Kokkonen a, Jaakko Räsänen a, Tapio Kotiaho c a VTT Processes, P.O. Box 1602, FI-02044 VTT, Finland b University of Helsinki, Faculty of Pharmacy, Drug Discovery and Development Technology Center (DDTC), P.O. Box 56, FI-00014 University of Helsinki, Finland c University of Helsinki,(More)
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