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OBJECTIVES The aim of the present study was to evaluate the performance of three different preoperative risk models in the prediction of postoperative morbidity and mortality in coronary artery bypass (CAB) surgery. METHODS Data on 1132 consecutive CAB patients were prospectively collected, including preoperative risk factors and postoperative morbidity(More)
The most serious infection after coronary artery bypass grafting (CABG) is mediastinitis following deep sternal wound infection. Antibiotic prophylaxis for at least 48 hours has been recommended. In this trial 551 consecutive patients were randomized to receive ceftriaxone in a single dose or cefuroxime thrice daily until the end of the second postoperative(More)
OBJECTIVE The release of proinflammatory cytokines has been shown to be associated with the development of complications after coronary artery bypass grafting with cardiopulmonary bypass. The purpose of the present study was to establish whether ischemic preconditioning (IP) could limit inflammatory cytokines release in patients undergoing elective coronary(More)
OBJECTIVE Cardiopulmonary bypass is acknowledged to be one of the major causes of a complex systemic inflammatory response after cardiac surgery, and it may contribute to postoperative complications and even multiple organ dysfunction. We here compared the cytokine responses and the degree of myocardial injury after coronary artery bypass grafting with or(More)
OBJECTIVE To investigate the anti-inflammatory and hemodynamic effects of 17beta-estradiol in men undergoing elective coronary artery bypass graft surgery (CABG). DESIGN Prospective, randomized, controlled. SETTING Operating room and intensive care unit in a university hospital. PARTICIPANTS Twenty-one men undergoing primary, elective CABG surgery. (More)
OBJECTIVE The Allen test is a widely used screening method of hand circulation. Our aim was to study whether the Allen test alone gives sufficient information for harvesting the radial artery in coronary artery bypass grafting. METHODS One hundred and forty-five patients scheduled for coronary artery bypass grafting underwent the Allen test, upper arm(More)
AIMS High-throughput metabolite quantification holds promise for cardiovascular risk assessment. Here, we evaluated whether metabolite quantification by nuclear magnetic resonance (NMR) improves prediction of subclinical atherosclerosis in comparison to conventional lipid testing. METHODS AND RESULTS Circulating lipids, lipoprotein subclasses, and small(More)
Hemodynamic instability is frequent after coronary surgery. The present study tested the hypothesis that inflammation, as determined by circulating cytokine levels, may contribute to the difficulty of controlling arterial blood pressure after coronary artery bypass grafting. A group of 44 male patients undergoing elective coronary artery bypass grafting(More)
OBJECTIVES We intended to investigate whether ischemic preconditioning (IP) enhances myocardial performance in patients who undergo off-pump coronary artery bypass grafting (CABG). DESIGN A controlled, randomized, prospective study. SETTING A university hospital. PATIENTS Thirty-two patients with left anterior descending coronary artery (LAD) or(More)
The objective of the present study is to determine the feasibility of chest computed tomography (CT) in screening for lung cancer among asbestos-exposed workers. In total, 633 workers were included in the present study and were examined with chest radiography and high-resolution CT (HRCT). A total of 180 current and ex-smokers (cessation within the previous(More)