Janusz Smigileski

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A mismatch repair gene hMSH2 (human mutS homolog 2) is involved in the correction of mispairing during replication, and its mutation is associated with both microsatellite instability and hereditary colorectal cancer. We have also evaluated its involvement in sporadic colorectal cancer tumorigenesis. The expression of hMSH2 was analysed in 75 cases of(More)
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