Janine Avemary

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The aim of the present study was the investigation of the mechanism, by which bradykinin B(2) receptor stimulation evokes an increase of the cytosolic Ca(2+) concentration in rat submucosal plexus. In ganglionic cells within the intact submucosal plexus, the Ca(2+)-response evoked by bradykinin was suppressed by Ni(2+), suggesting that Ca(2+) enters the(More)
Bradykinin acts as an inflammatory mediator in the gut. In the present study we characterized bradykinin-induced changes in the intracellular calcium concentration ([Ca(2+)](i)) in whole-mount submucosal preparations from rat distal colon and examined the bradykinin receptors and subsequent signalling cascades involved. Bradykinin (2.10(-10)-2.10(-7)mol/l)(More)
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