Janina Slodkowska

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Immunohistochemistry (IHC) plays an essential role in Pathology. In order to improve reproducibility and standardization of the results interpretation, IHC quantification methods have been developed. IHC interpretation based in whole slide imaging or virtual microscopy is of special interest. The objective of this work is to review the different(More)
The COST Action IC0604 "Telepathology Network in Europe" (EURO-TELEPATH) is an initiative of the COST (European Cooperation in the field of Scientific and Technical Research) framework, supported by the Seventh Framework Programme for research and technological development (FP7), of the European Union will be running from 2007 to 2011 and is aimed to(More)
The paper presents a combined method for an automatic hot-spot areas selection based on penalty factor in the whole slide images to support the pathomorphological diagnostic procedure. The studied slides represent the meningiomas and oligodendrogliomas tumor on the basis of the Ki-67/MIB-1 immunohistochemical reaction. It allows determining the tumor(More)
OBJECTIVE To evaluate the prognostic value of carcinoid angiogenesis for the presence of lymph node metastases, histologic subtype and tumor size. STUDY DESIGN The study group consisted of 72 resected primary lung carcinoids, 57 typical and 15 atypical. TNM staging was performed. The histologic criteria for carcinoids was based on the Flieder(More)
OBJECTIVE To determine the expression of two angiogenic factors, vascular endothelial growth factor (VEGF) and fibroblast growth factor receptors (FGFR), in non-small cell lung carcinoma (NSCLC) in relation to tumor stage (TN0, TN1, TN2) and in association with the expression of p53 protein, a potential suppressor of tumor angiogenesis. STUDY DESIGN The(More)
The paper presents the designed software CAMI (Computerized Analysis of Microscopic Images) for a digital reconstruction of the diversiform glands seen in chronic inflammatory gastric mucosa, and for automated recognition and quantization of the immunoreactive neuroendocrine (NE) cells appearing within mucosal glands. Digital reconstruction of the(More)
OBJECTIVE To present a computerized system for recognition of Fuhrman grade of cells in clear-cell renal cell carcinoma on the basis of microscopic images of the neoplasm cells in application of hematoxylin and eosin staining. STUDY DESIGN The applied methods use combined gradient and mathematical morphology to obtain nuclei and classifiers in the form of(More)
This paper presents modification of conventional watershed algorithm for cell segmentation in microscopic images of desmoglein-3 stained specimen. Presented method combines color deconvolution for ihc marker separation and GVF for watershed segmentation. Conventional watershed is highly noise sensitive, which often occurs in microscopy images. Suggested(More)
This report describes the clinical, radiological, microscopical and ligandohistochemical findings in a 17-year-old woman who suffered from an acute onset of pulmonary hemosiderosis after inhalation of pesticides used for the cultivation of strawberries. She complained of headache, dyspnea, rhinitis, weakness and recurrent severe hemoptysis. Chest(More)