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BACKGROUND Raised blood pressure is common in acute stroke, and is associated with an increased risk of poor outcomes. We aimed to examine whether careful blood-pressure lowering treatment with the angiotensin-receptor blocker candesartan is beneficial in patients with acute stroke and raised blood pressure. METHODS Participants in this randomised,(More)
BACKGROUND AND PURPOSE The purpose of the present study was to estimate the time trends of stroke during the last 10 years in an Estonian population by comparison of the results from the 2 previous stroke registries from Tartu. METHODS The Third Stroke Registry in Tartu was conducted from January 12, 2001, to November 30, 2003. The previous registry was(More)
OBJECTIVE To determine whether prestroke level of physical activity influenced stroke severity and long-term outcome. METHODS Patients included into the present analyses represent a subset of patients with first-ever stroke enrolled into the ExStroke Pilot Trial. Patients with ischemic stroke were randomized in the ExStroke Pilot Trial to an intervention(More)
The aim of the current study was to evaluate the outcome at 1 year following a first-ever stroke based on a population-based registry from 2001 to 2003 in Tartu, Estonia. The outcome of first-ever stroke was assessed in 433 patients by stroke risk factors, demographic data and stroke severity at onset using the Barthel Index (BI) score and the modified(More)
OBJECTIVES To provide information about the functional ability of the survivors of first-ever stroke in Estonia. PATIENTS AND METHODS A population based epidemiological study 1991 through 1993 in Tartu. Herewith the data for 1991 and 1993 are presented. A total of 519 persons were registered; 82% of them were admitted (mean length 14 days), 66% were(More)
OBJECTIVES The main goal of the Third Stroke Registry in Tartu was to determine the incidence and 28-day case-fatality of first-ever stroke in an Estonian population. SUBJECTS AND METHODS Stroke registry was conducted from 1 December 2001 to 30 November 2003. RESULTS The registry included 451 patients. The incidence rate of first-ever stroke(More)
OBJECTIVES To investigate if repeated verbal instructions about physical activity to patients with ischaemic stroke could increase long term physical activity. DESIGN Multicentre, multinational, randomised clinical trial with masked outcome assessment. SETTING Stroke units in Denmark, China, Poland, and Estonia. PARTICIPANTS 314 patients with(More)
BACKGROUND Patients with polio often experience new symptoms (muscle weakness, pain, fatigue and respiratory problems) many years after the acute disease. This study examined possible interactions between lifestyle factors (overweight, physical inactivity, smoking) and late polio with new symptoms. METHODS A total of 148 patients hospitalized for acute(More)
STUDY DESIGN Prospective clinical study. BACKGROUND The aim of the study was to investigate cortical reorganisation after traumatic spinal cord injury (TSCI) using functional magnetic resonance imaging (fMRI). SETTING Tartu University Hospital, Tartu, Estonia. METHODS We studied six right-handed tetraplegic TSCI patients at 1, 3 and 12 months after(More)
OBJECTIVES The study aimed to use functional magnetic resonance imaging to ascertain changes in sensorimotor system function in patients with hereditary spastic paraplegia and to correlate it with severity of spasticity and paresis. SETTING Tartu University Hospital, Tartu, Estonia. METHODS Nine patients with autosomal-dominant pure HSP and 14 age- and(More)