Janice Wheeler

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The group delay dispersion, also known as the attochirp, of high-order harmonics generated in gases has been identified as the main intrinsic limitation to the duration of Fourier-synthesized attosecond pulses. Theory implies that the attochirp, which is inversely proportional to the laser wavelength, can be decreased at longer wavelength. Here we report(More)
We report the compression of intense, carrier-envelope phase stable mid-IR pulses down to few-cycle duration using an optical filament. A filament in xenon gas is formed by using self-phase stabilized 330 microJ 55 fs pulses at 2 microm produced via difference-frequency generation in a Ti:sapphire-pumped optical parametric amplifier. The ultrabroadband 2(More)
Optimum conditions of pH, temperature and multiplicity of bacteriophage infection for the production of phage-associated lysin from Group C streptococci were defined. Lysin obtained by the optimum method was used to make protoplast membranes of Group A type 12 streptococci. These membranes consistently contained very low concentrations of rhamnose,(More)
High harmonic generation (HHG) is used to measure the spectral phase of the recombination dipole matrix element (RDM) in argon over a broad frequency range that includes the 3p Cooper minimum (CM). The measured RDM phase agrees well with predictions based on the scattering phases and amplitudes of the interfering s- and d-channel contributions to the(More)
A monoclonal antibody reactive against amyloid P component (NCL-AMP) has been developed following immunization of mice with partially-purified human glomerular basement membranes (GBM) and standard hybridization and cloning techniques. The antibody reactivity was evaluated by enzyme-linked immunosorbent assay (ELISA) and by the indirect immunoperoxidase(More)
Cellular and humoral responses were ivestigated following human glomerular basement membrane a-d streptococcol Type 12 membrane injections in rabbits. Using the leucocyte migration inhibition test and double diffusion in agar gel, cross-reactivity between the antigens was evident, though neither antigen induced significant proteinuria or nephritis in the(More)
A double immunohistochemical labelling procedure in paraffin-embedded renal tissue is reported in which CD3 was targeted as a T cell marker and Ki67 as a marker of cell proliferation. Proliferating and quiescent T cells were unequivocally identified in situ, and their precise location within the kidney was clarified by the use of periodic acid-Schiff(More)
Electron backscatter diffraction (EBSD) is based on the principle that a beam of electrons generated in the scanning electron microscope (SEM) is the source of randomly scattered electrons in a specimen. The backscattered electrons (BSE) that escape the sample generate a Kikuchi pattern on a phosphor screen, which is linked to the specimen crystal(More)
An approach is presented to experimentally constrain previously unreachable (p, γ) reaction rates on nuclei far from stability in the astrophysical rp process. Energies of all critical resonances in the (57)Cu(p,γ)(58)Zn reaction are deduced by populating states in (58)Zn with a (d, n) reaction in inverse kinematics at 75 MeV/u, and detecting γ-ray-recoil(More)
A method is reported forin vivo bromodeoxyuridine incorporation in mice and its subsequent visualization in kidney by immunohistochemistry. Following formal-sublimate fixation of the kidney, bromodeoxyuridine labelled nuclei were detected in paraffin sections with a monoclonal antibody and visualized by an immunoperoxidase technique. This rapid and(More)