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We describe the detection characteristics of a device the Resonant Coil Magnetometer (RCM) to quantify paramagnetic particles (PMPs) in immunochromatographic (lateral flow) assays. Lateral flow assays were developed using PMPs for the measurement of total prostate specific antigen (PSA) in serum samples. A detection limit of 0.8 ng/mL was achieved for total(More)
The paper presents a rapid immunoassay system capable of quantifying analyte in complex biological and environmental media. Antibody-coated micrometer-sized paramagnetic particles are used as labels in an assay in which they bind quantitatively with an analyte and capture antibody molecules immobilized on a polyester disk to form a sandwich assay. The assay(More)
Magnetic immunoassays have been shown to have similar detection limits to conventional immunoassays, with the advantage of reduced total assay time. The aim of this study was to demonstrate that an integrated lysis and measurement system could be used to quantitatively measure intracellular target molecules using prostate specific antigen as a model(More)
In this article a new approach to planning of a nonholonomic motion is presented. A flexible, intelligent planner based on a static map and the topology of the robot's environment has been developed. The approach uses 'particles' to construct automatically a path between two given locations. The generated path is a smooth trajectory, where the length of the(More)
The use of industrial scale experimental machinery robot systems such as the Mitsubishi RV-2AJ manipulator in research to experimentally prove new theories is a great opportunity. The robot manipulator communications and control framework written in Java simplifies the use of Mitsubishi robot manipulators and provides communication between a personal(More)
A novel, integrated lysis and immunoassay methodology and system for intracellular protein measurement are described. The method uses paramagnetic particles both as a lysis agent and assay label resulting in a rapid test requiring minimal operator intervention, the test being homogeneous and completed in less than 10 min. A design study highlights the(More)
The manufacturing industry today is still focused on the maximization of production. A possible development able to support the global achievement of this goal is the implementation of a new support system for trajectory-planning, specific for industrial robots. This paper describes the trajectory-planning algorithm, able to generate trajectories manageable(More)
A measuring instrument plays important role in the biomedical measurement since the biological process in living organism generates very weak signal. Therefore, a reliable and sensitive measuring instrument is needed. In this study, a lock-in amplifier was analysed and tested. This paper presents an experiment to investigate the lock-in amplifier for(More)