Janice Fletcher

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BACKGROUND Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency is the disorder thought most to justify neonatal screening by tandem-mass spectrometry because, without screening, there seems to be substantial morbidity and mortality. Our aim was to assess the overall effectiveness of neonatal screening for MCAD deficiency in Australia. METHODS We(More)
Sperm samples from a carefully matched group of 43 cigarette smokers and 43 non-smokers attending an infertility clinic were examined for morphological abnormality. The smokers were found to have a significantly greater percentage of abnormal forms. In the light of other work showing increased chromosome damage in blood lymphocytes of cigarette smokers and(More)
OBJECTIVE To explore the verbal communication of child care providers regarding preschool children's internal and non-internal hunger and satiation cues. METHODS Video observation transcripts of Head Start staff (n=29) at licensed child care centers in Colorado, Idaho, and Nevada were analyzed for common themes. RESULTS Adults' verbal communication with(More)
INTRODUCTION Strategies to prevent adult chronic diseases, including obesity, must start in childhood. Because many preschool-aged children spend mealtimes in child care facilities, staff should be taught supportive feeding practices for childhood obesity prevention. Higher obesity rates among low-income children suggest that centers providing care to these(More)
Any opinions, findings, conclusions, or recommendations expressed in this publication are those of the authors and do not necessarily reflect the view of the U.S. Department of Agriculture. Acknowledgments Thank you to the many child care center and Head Start programs that graciously allowed us to videotape mealtimes. Thank you also to the early childhood(More)
INTRODUCTION In this study, we aimed to evaluate whether fasting plasma citrulline concentration predicts subsequent glucose absorption in critically ill patients. METHODS In a prospective observational study involving 15 healthy and 20 critically ill subjects, fasting plasma citrulline concentrations were assayed in blood samples immediately prior to the(More)
Some people call it " family style service. " Others call it " children serving themselves. " We like to call it " community style service. " Whatever you call it, it means that containers of food are put on the table. Then, children pass a common container around the table, each taking some for their plates. Sometimes a whole meal is available for children(More)
Prostaglandin (PG)D2 has been shown to be an active agent in the resolution of experimentally induced inflammation. This study was undertaken to determine the presence of PGD2 in chronic joint effusions and to explore the potential contributions of dendritic cells (DC) and monocytes to the intra-articular synthesis of PGD2. Synovial fluid (SF) was obtained(More)