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  • Jangsoon Lee, Soon young Park, +8 authors Hoi Young Lee
  • Biology, Medicine
  • Clinical Cancer Research
  • 2006 (First Publication: 1 November 2006)
  • Purpose: Lysophosphatidic acid (LPA) plays an important role in mediating cell proliferation, survival, and tumor invasion and angiogenesis. This bioactive phospholipid at the concentration inExpand
  • In Duk Jung, Jangsoon Lee, +7 authors Hoi Young Lee
  • Medicine, Biology
  • European journal of biochemistry
  • 2004 (First Publication: 1 April 2004)
  • Lysophosphatidic acid (LPA), one of the naturally occurring phospholipids, stimulates cell motility through the activation of Rho family members, but the signaling mechanisms remain to be elucidated.Expand
  • Jangsoon Lee, Chandra Bartholomeusz, +4 authors Naoto T. Ueno
  • Medicine
  • Breast Cancer Research and Treatment
  • 2014 (First Publication: 12 June 2014)
  • Although there are effective HER2-targeted agents, novel combination strategies in HER2-overexpressing breast cancers are needed for patients whose tumors develop drug resistance. To develop newExpand
  • Jangsoon Lee, In Duk Jung, Chang Gyo Park, Jeung-Whan Han, Hoi Young Lee
  • Medicine
  • Melanoma research
  • 2006 (First Publication: 1 October 2006)
  • Autotaxin, a lysophospholipase D producing lysophosphatidic acid, augments invasive and metastatic potential of tumor cells. Current investigations have focused on understanding the molecularExpand