Jang Wook Sohn

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OBJECTIVES To evaluate the effects of transfusions in patients with severe sepsis and septic shock on mortality. DESIGN Propensity-matched analysis of a prospective observational database (April 2005 to February 2009). SETTING Twenty-two medical and surgical intensive care units in 12 teaching hospitals in Korea. PATIENTS One thousand fifty-four(More)
OBJECTIVES The high prevalence of methicillin-resistant Staphylococcus aureus (MRSA) coupled with an increase in vancomycin use have induced vancomycin tolerance in MRSA, adversely affecting the outcome of MRSA bacteraemia. This study aimed to identify predictors of persistent MRSA bacteraemia (PMRSAB) in patients treated with vancomycin. METHODS A(More)
BACKGROUND Despite the increasing popularity of acupuncture, the importance of infection control is not adequately emphasized in Oriental medicine. In December 2001, an Oriental medical doctor in Seoul, South Korea, encountered several patients with persistent, culture-negative skin lesions on the trunk and extremities at the sites of prior acupuncture(More)
Acinetobacter baumannii has been increasingly reported as a significant causative organism of various nosocomial infections. Here we describe an outbreak of carbapenem-resistant A. baumannii (CRAB) in the ICUs of a Korean university hospital, along with a successful outbreak control program. From October 2007 through July 2008, CRAB was isolated from 57 ICU(More)
Carbapenem-resistant Klebsiella pneumoniae isolates producing K. pneumoniae carbapenemases (KPC) were first reported in the USA in 2001, and since then, this infection has been reported in Europe, Israel, South America, and China. In Korea, the first KPC-2-producing K. pneumoniae sequence type (ST) 11 strain was detected in 2010. We report the case of a(More)
BACKGROUND Streptococcus pneumoniae causes a broad spectrum of illnesses ranging from mild upper respiratory tract infections to invasive pneumococcal disease (IPD). Quantitative data on the burden of pneumococcal disease, important for the establishment of appropriate vaccination strategies, is currently lacking in adults. METHODS This multicenter,(More)
OBJECTIVES To evaluate the clinical outcome and predictive factors of recurrence among patients with Kikuchi's disease. METHODS Between January 2001 and December 2006, all patients with Kikuchi's disease were included in the study. Data were collected on co-morbidities, clinical manifestations, and ultrasound/laboratory findings, and the differences were(More)
STUDY DESIGN A retrospective study examining the clinical features, management, and treatment outcome of patients with spinal tuberculosis (TB). OBJECTIVE To determine the influence of disease severity and treatment modality on outcome of patients with spinal TB. SUMMARY OF BACKGROUND DATA Although anti-TB chemotherapy is now the mainstay treatment for(More)
OBJECTIVES The time to positivity (TTP) of blood cultures is associated with the microbial load in the blood and prognosis in patients with bloodstream infections caused by various bacterial species. However, relevant information about the TTP for Candida species in candidaemia is limited. We investigated the clinical impact of the TTP on mortality in(More)
OBJECTIVES The aim of this study was to evaluate the control of extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae and antimicrobial resistance through a computerized antibiotic control program. METHODS An ambidirectional intervention study was conducted at a 750-bed university hospital in Korea from February 2004 to April 2006. In(More)