Janet R Christensen

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Anatomical evidence of brain damage from electroconvulsive therapy (ECT) is lacking; but there are no modern stereological studies in primates documenting its safety. Magnetic seizure therapy (MST) is under development as a less invasive form of convulsive therapy, and there is only one prior report on its anatomical effects. We discerned no histological(More)
Hippocampal atrophy and neuron loss are early and reproducible findings in Alzheimer's disease, and recent magnetic resonance imaging studies indicate that hippocampal atrophy may also be present in Parkinson's disease (PD). To determine whether or not cell loss occurs in PD, we estimated the total neuron and glial cell numbers as well as the total volume(More)
Bonding composite resin to enamel of teeth affected by amelogenesis imperfecta (AI) is often problematic, especially in cases with poorly mineralized, friable enamel. Difficulty in bonding hypomineralized enamel can significantly limit the restorative and orthodontic treatment options for AI patients. In this report, we document a novel approach to bonding(More)
A lever-release version of the conditioned avoidance response (CAR) task was used to assess the behavioral effects of several psychomotor stimulants in rats. The indirect dopamine agonists,d-amphetamine (0.1 and 0.25 mg/kg) and cocaine (7.5 and 15 mg/kg), enhanced performance on this task. Both drugs incre ased percent avoidance responses and decreased(More)
OBJECTIVE To test the life-sparing and therapeutic effect of a parenterally administered virus-specific antiviral phosphorodiamidate morpholino oligomer (PMO) for treating kittens during outbreaks of severe viral disease. ANIMALS 112 kittens of various sex and age in 4 trials involving 3 outbreaks of naturally developing caliciviral disease. PROCEDURES(More)
Recent epidemiological studies suggest that chronic exposure to nitrous oxide may be a health hazard to the dental staff and the ADA has recommended that atmospheric nitrous oxide be controlled by use of a scavenging system. These concerns are of special interest to pediatric dentists because studies have shown that the effectiveness of the scavenging(More)
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