Janet M Burlingame

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OBJECTIVE Obstetric anal sphincter injury (ASI) is associated with significant morbidity We conducted an ASI workshop for 20 obstetrics and gynecology residents and assessed its impact. Our goal was to determine and enhance residents' knowledge using a multimedia presentation, hands-on simulator and tests. We comment on trends regarding residents' knowledge(More)
Cyclins are proteins that support the progression of cell-cycle stages in proliferating cells. The purpose of this study was to determine which of the cyclin genes is involved in the regulation of normal human trophoblast proliferation. The presence and cellular localization of four G1 cyclins D1, D2, D3 and E, were determined by immunohistochemistry. This(More)
OBJECTIVE To identify the presence and/or absence of reactive oxygen species and total antioxidant capacity in amniotic fluid and to determine changes in the levels of reactive oxygen species and total antioxidant capacity with advancing gestational age of pregnancy and fetal or neonatal weights. METHODS Amniotic fluid was collected from a total of 26(More)
Objective:The objective of this study was to report thoracic impedance cardiography (ICG) measurements and compare them with echocardiography (echo) measurements throughout pregnancy and in varied maternal positions.Method:A prospective cohort study involving 28 healthy parturients was performed using ICG and echo at three time points and in two maternal(More)
We report a case series that lends support for both the maternal and neonatal safety of vaginal delivery in pregnancies complicated by heritable von Willebrand disease types 2A and 2B. With proper hematologic support, a cesarean delivery may be indicated only for obstetric reasons.
AIM To describe the effects of nifedipine tocolysis on blood pressure and heart rate in non-hypertensive women. METHODS This was a retrospective study from 2001 to 2011 to compare blood pressures and heart rates among non-hypertensive women on nifedipine tocolysis up to 8 h after nifedipine initiation. Measurements at 20-60 and 61-120 min were compared to(More)
OBJECTIVE To determine whether group B Streptococcus (GBS)-colonized pregnant women who report a history of penicillin allergy can safely undergo diagnostic evaluation to rule out or confirm the potential for an IgE-mediated (allergic) reaction to penicillin. STUDY DESIGN Over 18 months, all pregnant women with GBS-positive vaginal/rectal cultures and a(More)
OBJECTIVE To measure amniotic fluid levels of vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), and transforming growth factor (TGF)-beta2 and to characterize their levels with respect to advancing gestational age and pregnancy-related complications. STUDY DESIGN Amniotic fluid was collected from a total of 37 patients, 2(More)
BACKGROUND Pregnancy has a potentially deleterious affect on moyamoya disease (MMD), a cerebrovascular condition characterized by spontaneous occlusion of the distal internal carotid arteries resulting in the neoangiogenesis of fragile collateral blood vessels. The disease renders patients susceptible to both hemorrhagic and ischemic stroke. METHODS A(More)