Janet L. Parkin

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Although single-channel electrode arrays implanted in the scala tympani of deaf patients are useful as an aid to lip reading and for distinguishing some environmental sounds, they do not transmit intelligible speech. However, multichannel electrode arrays, which take advantage of the cochlea's tonotopic organization, may be capable of generating the complex(More)
A retrospective analysis using patient and family questionnaires and chart review was done on 269 patients with head and neck neoplasms. Sixty-nine with tumors at sites known to be unrelated to tobacco and alcohol use served as controls. Two hundred patients with epidermoid carcinoma of the oral cavity, pharynx, and larynx constituted the study group.(More)
The purpose of this report is to compare temporal bone computed tomography (CT) to high-resolution magnetic resonance (MR) imaging using a novel thin-section fast spin echo (FSE) pulse sequence in identifying and characterizing patients with large vestibular aqueduct syndrome. Sixteen patients with sensorineural hearing loss and a CT diagnosis of large(More)
A patient who uses the Ineraid cochlear implant, and who has hearing thresholds less than 50 dB HL for frequencies under 500 Hz in his nonimplanted ear, was asked to match the pitch of low-frequency signals presented to his two ears. The patient produced pitch matches, for frequencies of 125, 200, and 300 Hz presented to his most apical electrode, that were(More)
The acute leukemia associated with the t(4;11) chromosome rearrangement is characterized by relatively consistent clinical features: occurrence primarily in young individuals, hyperleukocytosis, and poor response to therapy. This study describes the morphological, ultrastructural, and immunologic characteristics of the leukemic cells from ten patients with(More)
Patients who use the Ineraid cochlear implant were tested in four experiments with materials which assessed frequency discrimination and speech understanding. In each experiment both frequency discrimination and speech recognition varied among patients. Correlations between the two measures were significant and ranged from 0.60 to 0.83. Most generally,(More)
PURPOSE To evaluate a high-resolution, thin-section fast spin-echo MR imaging technique of the inner ear to identify the large vestibular aqueduct syndrome seen on temporal bone CT scans. METHODS We retrospectively reviewed the temporal bone CT scans of 21 patients with hearing loss and enlarged bony vestibular aqueducts by CT criteria. High-resolution(More)
PURPOSE To determine whether unenhanced high-resolution T2-weighted fast spin-echo MR imaging provides an acceptable and less expensive alternative to contrast-enhanced conventional T1-weighted spin-echo MR techniques in the diagnosis of acoustic schwannoma. METHODS We reviewed in a blinded fashion the records of 25 patients with pathologically documented(More)
A cell line, designated RS4;11, was established from the bone marrow of a patient in relapse with an acute leukemia that was characterized by the t(4;11) chromosomal abnormality. The cell line and the patient's fresh leukemic cells both had the t(4;11)(q21;q23) and an isochromosome for the long arm of No. 7. Morphologically, all cells were lymphoid in(More)
A survey of telephone use by 66 patients fitted with the Ineraid cochlear prosthesis revealed that 51% initiate telephone calls (most calls are to family or friends) and that 66% answer the telephone. Of the patients who answer the telephone, 49% indicated that they could identify the gender and/or age of the caller most of the time, 27% could identify a(More)