Janeiro M C Perez

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Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are sporadic neurodegenerative diseases presenting as atypical parkinsonian disorders, characterized by the presence of tau-positive neurofibrillary tangles. Recently, an extended haplotype (H1E) of 787.6 kb that comprises several genes including MAPT showed increased association with(More)
We performed a case-control study of acute renal failure (ARF) in patients hospitalized with sickle cell anemia (SCA). Twelve of the 116 patients (10.3%) whose records were suitable for analysis were diagnosed as having ARF based on a minimum of doubling of their serum creatinine levels (mean rise was 205 +/- 49%). ARF patients were more likely to have been(More)
Translocation (14;18)(q32;q21) has been shown to be present in diagnostic tissue specimens from approximately 85% of patients with follicular lymphoma (FL) and 30% with diffuse non-Hodgkin lymphomas (NHL) in the USA. Also, there is evidence that the distribution of NHL subtypes differs by geographic region; however, there are no data for Ecuador. Using(More)
DNA common variants may significantly contribute to genetic risk for common diseases. Because of its biological function in DNA repair, hMSH2 gene polymorphisms are candidates for influencing cancer susceptibility and overall genetic stability. Twenty-two individuals with non-Hodgkin lymphomas (NHL) and 50 normal individuals were screened for polymorphic(More)
There are few reports about the incidence of the DeltaF508 mutation in Latin American countries. We show the study of the DeltaF508 mutation and the seven most common "European" mutations in 10 Ecuadorian CF affecteds. The incidence of DeltaF508 mutation found was 25% and none of the other seven was detected in our population, which indicates that at least(More)
To evaluate the effect of manual lymphatic drainage on technetium-99m-labeled dextran (99mTcDx) transport, 16 patients with lymphedema of lower extremities underwent two lymphscintigraphy exams by injecting 99mTcDx intradermally into the first interdigital space of the affected extremity. The first was a control examination at rest followed by an(More)
Telomeric association (TA), i.e. fusion of chromosomes by their telomeres, predisposes a cell to genetic instability. Because of this we investigated the effect of X-rays exposure and cigarette smoking on the frequency of TA in peripheral blood lymphocytes of exposed individuals, in order to determine if TA can be a chromosomal marker in populations exposed(More)
The pneumocephalus is commonly encountered after neurosurgical procedures. The collections are usually small with benign behavior, and they respond to a conservative therapy. However, there is a high percentage of cases that may behave like a space-occupying lesion. A high index of suspicion is necessary to make the diagnosis and prompt treatment of these(More)