Jane Williams

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Endoplasmic reticulum oxidoreductases (Eros) are essential for the formation of disulfide bonds. Understanding disulfide bond catalysis in mammals is important because of the involvement of protein misfolding in conditions such as diabetes, arthritis, cancer, and aging. Mammals express two related Ero proteins, Ero1alpha and Ero1beta. Ero1beta is(More)
PURPOSE/OBJECTIVES To describe the experience of alopecia in people undergoing chemotherapy. DESIGN Qualitative. SAMPLE Using announcement flyers, 15 participants (13 women and 2 men) were recruited to participate in audiotaped, in-depth interviews. METHOD In-depth interviews and narrative analysis of participants' "stories" using a sociolinguistic(More)
Faculty at a baccalaureate nursing program at a state college discuss a multifaceted approach to meeting the needs of a very diverse student population. These students reflect the changing demographics of the state and their education contributes to providing a racially, ethnically, and culturally diverse nursing workforce. The program addresses multiple(More)
My work covers four domains: Expert clinical practice Working within a critical companionship model has enabled me to challenge practice at the bedside. Reflective sessions within stroke care areas allow me to hear about difficulties staff face and, in turn, for me to challenge practice. Professional leadership and consultancy As a member of the(More)
Selenium, a trace element that is fundamental to human health, is incorporated into some proteins as selenocysteine (Sec), generating a family of selenoproteins. Sec incorporation is mediated by a multiprotein complex that includes Sec insertion sequence-binding protein 2 (SECISBP2; also known as SBP2). Here, we describe subjects with compound heterozygous(More)
BACKGROUND Stroke produces many effects that impact eating. Nutrition is fundamental for recovery and rehabilitation, but the nursing nutritional role and associated outcomes have not been delineated. AIMS (1) To identify nursing interventions intended to improve nutritional status and related outcomes of stroke survivors, and (2) To examine the outcomes(More)
A series of cyclometalated platinum(II) complexes have been prepared, [PtL(n)Cl], containing N--C--N-coordinating, terdentate ligands based on 1,3-dipyridylbenzene (HL(1)), incorporating aryl substituents at the central 5 position of the ligand. All of the new complexes are intensely luminescent in a degassed solution at 298 K (phi = 0.46-0.65 in(More)
The remarkable luminescence properties of the platinum(II) complex of 1,3-di(2-pyridyl)benzene, acting as a terdentate N=C=N-coordinating ligand cyclometalated at C2 of the benzene ring ([PtL(1)Cl]), have been investigated, together with those of two new 5-substituted analogues [PtL(2)Cl] and [PtL(3)Cl] [HL(2) = methyl-3,5-di(2-pyridyl)benzoate; HL(3) =(More)
This work explores time-resolved emission imaging microscopy (TREM) for noninvasive imaging and mapping of live cells on a hitherto uncharted microsecond time scale. Simple robust molecules for this purpose have long been sought. We have developed highly emissive, synthetically versatile, and photostable platinum(II) complexes that make TREM a practicable(More)
This article briefly explores the literature focusing on early childhood development, parenting and the provision of health services to young families. It highlights a number of reasons why some children with subtle developmental difficulties are not identified until school age. Relevant to child health nurses are: a changing focus on early childhood health(More)